background: glybenclamide and metformin are two of the most common oral hypoglycemic drugs which are often used in treatment of type ii diabetes mellitus. toxicity due to these drugs may occur intentionally, accidentally, or even at the normal dosage because of the progression of such internal diseases as renal dysfunction. methods: in this case series study, 59 patients poisoned with oral hypo...

Objective: To evaluate drug utilization pattern of oral hypoglycemic agents in Type-2 diabetic outpatients. Materials and Methods: A prospective study was carried out in 202 out patients for a period of 9 months in a tertiary care hospital. Patients treated with oral hypoglycemic agents were used for the study. The demographic data, disease data and utilization of different classes of oral hypo...

background: candidal colonization in complete denture wearers is a commonly encountered condition that worsens in the presence of untreated diabetes mellitus. the aim of this study was to evaluate the correlation between oral candidiasis in denture‑bearing mucosa and elevated blood glucose levels in complete denture wearers and to evaluate the effect of oral hypoglycemic drug therapy in control...

Herbs and herbal products are considered to be safer and people mix it often with the oral hypoglycemic agent in diabetes therapy. But numerous reports say that every combination of herbs and drugs is not safe. Some combinations may be beneficial and some may be harmful also. So before taking any herbal remedies with oral hypoglycemic agent, patient should consult physician. In this paper we ar...

BACKGROUND Hypoglycemic coma is a continuous threat for diabetic patients treated with insulin and/or oral hypoglycemic agents; it may be associated with substantial morbidity and mortality. METHODS We retrospectively reviewed our clinical experience with drug-induced hypoglycemic coma during a 7-year period. RESULTS The study consisted of 102 patients and included 61 females and 41 males. ...

Antituberculosis (anti-TB) treatment may be affected by both diabetes and hypoglycemic agents in patients with these 2 comorbidities. However, data supporting this conclusion relate only to standard anti-TB therapies. Sirturo® (bedaquiline) and Deltyba® (delamanid), novel drugs for multidrug-resistant tuberculosis (MDR-TB), are recommended for diabetes patients when another effective treatment ...

BACKGROUND AND OBJECTIVE Oxidative stress plays an important role in pathogenesis of diabetes mellitus and its complications. Our previous study has shown glucose lowering effect produced by 3 months supplementation of Nigella sativa (NS) in combination with oral hypoglycemic drugs among type 2 diabetics. This study explored the long term glucose lowering effect (over one year) of NS in patient...