offshore pipelines are an effective tool for transportation of oil and gas which are usually assembled by the use of girth welds. since flaws may naturally exist at such welds, fracture assessment of girth welded offshore pipelines is substantial. current fracture assessment procedures like bs 7910 consider identical material properties for the weld and the base metals. however the strength dif...

This paper discusses the strength mis-match effect on cleavage fracture of notched materials based on the local approach. The aim of the study is to verify the independence of the critical Weibull stress at fracture on the strength mis-match condition. Diffusion bonded joints were made with two materials S and H different in strength level. Two types of 3-point bend specimen were extracted. One...

Background: Diet quality indices address the diet’s complexity and are calculated by a combination of foods and/ or nutrients which together represent a dietary pattern. The current study analysed the relationship between the common carotid artery intima media thickness (cIMT), the presence of plaque and the carotid target organ damage (cTOD) with the diet quality assessed through the Diet Qual...

The aim of this study was to increase the in vivo mean residence time of vinpocetine after IV injection utilizing long circulating mixed micellar systems. Mixed micelles were prepared using Pluronics L121, P123 and F127. The systems were characterized by testing their entrapment efficiency, particle size, polydispersity index, zeta potential, transmission electron microscopy and in vitro drug r...

Objectives: In this present study the hepatoprotective effect of an optimized herbal formula (HF) was appraised against paracetamol induced liver damage in rats. Methods: In vitro antioxidant activity HF evaluated by ABTS radical scavenging assay. The (100, 200 and 400 mg/kg b.w) assessed Serum enzymatic levels serum glu...

The fatigue crack growth-rate test of rail head, waist, and bottom material for U71Mn welded was carried out. Digital image correlation (DIC) used to capture the full-field displacement. crack-tip position accurately obtained based on displacement data, an accurate opening (CTOD) measurement point found. CTOD values head under overloaded unloaded condition were extracted, area size elastic plas...

Poor water solubility of a drug is a major challenge in drug delivery research and a main cause for limited bioavailability and pharmacokinetic parameters. This work aims to utilize custom fractional factorial design to assess the development of self-nanoemulsifying drug delivery systems (SNEDDS) and solid nanosuspensions (NS) in order to enhance the oral delivery of atorvastatin (ATR). Accordi...