background:naltrexone is a competitive opioid receptor antagonist blocking the euphoric effects of exogenous opioids. when used concomitantly with opioids, naltrexone causes severe withdrawal symptoms.the main aim of the study is to determine the symptomatology and outcome of patients who consumed naltrexone in conjunction with an opioid substance. methods:this cross-sectional study was perform...

background : the existing evidence about the clinical situations of the bipolar patients with opioid dependence is scarce. the present study was carried out to compare the clinical features and course of the bipolar disorder type i regarding the two subgroups of opioid dependent and non-dependent. methods : there were 178 adult patients with bipolar disorder type i consecutively referred to the...

objective: the aim of this study was to examine the difference of early maladaptive schemas and parenting origins in opioid abusers and non-opioid abusers. method: the early maladaptive schemas and parenting origins were compared in 56 opioid abusers and 56 non-opioids abusers. schemas were assessed by the young schema questionnaire 3rd (short form); and parenting origins were assessed by the y...

ultra rapid opioid detoxification (urod) is one of the new methods of detoxification. this method of detoxification involves putting patients under general anesthesia and actively giving them opioid antagonists. the objective of this study was to evaluate effects of anesthesia duration in urod on severity of withdrawal syndrome. sixty addicted patients seeking urod procedure assigned randomly t...

results the most common drug used by 48 women (81.35%) was th eopium, followed by crack(8.47%), heroin (1.69%), methadone (1.69%)and cannabis (1.69%). mean age of the first time experience of cigarette smoking was 17.11 ± 9.22 years. also, the mean age of the first time drug substance use was 27.62 ± 10.46 years and the mean duration of drug use was 5.2 ± 12.0 years. among studied women, 74.57%...

Abstract Background: Tramadol is a centrally acting opioid analgesic used to treat moderate to sever pain. It has more advantage and less opioid adverse effects than conventional opioid analgesia. Case Report: This article reports a patient with tramadol dependency that had psychosis after tramadol withdrawal. Conclusion: By the increase of tramadol usage for relief of chronic pain, t...

The past decade has seen a marked increase in the illicit use of opioids, as well as a doubling of the percentage of individuals seeking treatment for opioid use disorders. However, little is known about the differences between opioid users and nonopioid users in residential treatment. Further, no studies have been published that compare opioid users and nonopioid users in treatment for co-occu...

A central question in prescribing opioids for chronic non-cancer pain (CNCP) is how to best balance the risk of opioid abuse and dependence with the benefits of pain relief. To achieve this balance, clinicians need an understanding of the risk factors for opioid abuse, an issue that is only partially understood. We conducted a secondary data analysis of regional VA longitudinal administrative d...

Opioids, amphetamines, and other types of substances have been widely abused around the world. Opioid dependence and tolerance are two distinct phenomena that have been associated with substance abuse issues. The management of its adverse consequences is becoming more challenging. More and more people are treated in Methadone Maintenance Therapy (MMT) program yet the issues are still unresolved...