objective(s)the purpose of this study holds, for the first time, an evaluation of the intraperitoneal curcumin lavage on the development of post-operative intra-abdominal adhesions.materials and methodsthirty male wistar rats were randomized into five groups. the rats were administered anesthesia and underwent surgery in order to create intra-abdominal adhesions. before the abdomen was closed, ...

P-glycoprotein (P-gp) is encoded by the multidrug resistance (MDR1) gene and is well studied as a multi-drug resistance transporter. Peritoneal adhesion formation following abdominal surgery remains an important clinical problem. Here, we found that P-gp was highly expressed in human adhesion fibroblasts and promoted peritoneal adhesion formation in a rodent model. Knockdown of P-gp expression ...

Objective(s)The purpose of this study holds, for the first time, an evaluation of the intraperitoneal curcumin lavage on the development of post-operative intra-abdominal adhesions.Materials and MethodsThirty male Wistar rats were randomized into five groups. The rats were administered anesthesia and underwent surgery in order to create intra-abdominal adhesions. Before the abdomen was closed, ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : adhesions, as abnormal scared tissue, are common following gynecological operations and can cause chronic pelvic pain, infertility, poor outcomes of future surgeries, and intestinal obstruction. oxygen free radicals are known as one of the main causes of adhesion formation. this study is to evaluate the effect...

objective(s): abdominal adhesions are one of the most important problems, occurring after intra-abdominal surgery in more than 90% of cases. this condition is the leading cause of bowel obstruction, infertility, and abdominal/pelvic pain. gold nanoparticles (gnps) have been shown to be non-toxic and exhibit anti-inflammatory, anti-angiogenic and antioxidant activities. the purpose of this study...

  Objective- Mechanisms that decrease oxidative stress and enhance peritoneal fibrinolysis reduce adhesions. N-acetyl-L-cysteine (NAC) is an antioxidant whose effect on peritoneal fibrinolysis in large animal model has not been established. The aims of this study were to investigate the ability of NAC to decreased adhesion in stablished model of serosal trauma in sheep. Design- Expe...

Background & aims: Adhesion and fibrotic bands formation is one of the most important post-surgical complication in pelvic and abdominal surgeries. Major studies in prevention of adhesion formation have based on antioxidant and anti-inflammatory agents. Silymarin, Silybum marianum extract contains compounds with antioxidant, anti-inflammatory and fibrinolytic activities thus could reduce adhesi...

The objective of this study was to determine the effectiveness of topical administration of honey in prevention of or reduction in post-surgical peritoneal adhesions in dog. The study was conducted on 18 adultfemale mixed-breed dogs with a mean ± SD weight of 20 ± 4.25 kg. A standardized surgical trauma (serosaltrauma model) was made in the dogs’ descending colon to induce adhesion formation. T...

introduction: adhesion formation after pelvic surgery is still a major cause of several morbidities such as infertility, pain, bowel obstruction and subsequent intra-operative complications. our aim was to investigate the effects of d-penicillamine in preventing adhesion formation in rat uterine horn. methods: this experimental trial was conducted on 30 rats. the rats were randomly assigned to ...