Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...

Cardiac sodium channels are integral membrane proteins whose structure is not known at atomic level yet and their molecular kinetics is still being studied through mathematical modeling. This study has focused on adapting an existing model of cardiac Na channel to analyze molecular kinetics of channels at 9-37°C. Irvine et al developed a Markov model for Na channel using Neuronal Network Model ...

the purpose of this paper is to present a 2d depth-averaged model for simulating and examining unsteady flow patterns in open channel bends. in particular, this paper proposes a 2d depth-averaged model that takes into account the influence of the secondary flow phenomenon through calculation of the dispersion stresses. the dispersion terms which arose from the integration of the product of the ...

secondary flow investigation could be regarded as an important issue in open channel flow, in spite of its lower quantity compared to the base flow in the water course. it should be given special consideration because of the influence on some hydraulic factors in open channel, specifically in compound channels. in compound channels' due to the difference in the flow velocity of the main ch...

conclusions ip injection of cb1 receptor antagonist might have an anxiogenic profile in rat, whereas calcium channel blocker attenuated the anxiogenic effect of am251. our results suggest that there is an interaction between functions of l-type ca2+ channels and cannabinoid system in anxiety. background the elevated plus-maze (epm) has been broadly used to investigate anxiolytic and anxiogenic ...

An innovative Volumetric Current Meter (VCM) was designed in order to allow quick velocity measurements in open channels. At first, the coefficient of velocity (Cv) of the device was determined through calibration under different water velocities in the laboratory. The measurement performance was verified by measurements performed in similar flows in irrigation channels using an ordinary curren...

water distribution method based on the type of water conduits can be divided into two groups, namely, open and closed systems, while on the basis of the energy of the water flow, the two groups are gravity flow and pressurized flow. open channel type conveyance and distribution is achieved by gravity and includes channels made by embankment construction, excavation, or construction of prefabric...

This study makes use of the Tsallis entropy to predict the shear stress distribution. Given a definition of the Tsallis entropy, it is maximized by using the probability density function, which then is used to attain a novel shear stress equation. This is then employed for calculating the shear stress distribution in rectangular channels in different aspect ratios and finally, for viability, th...