نتایج جستجو برای: omics
تعداد نتایج: 6640 فیلتر نتایج به سال:
Completion of the human genome project revealed that the molecular mechanisms of cellular responses to different situations cannot be predicted from the sequence of their genes. Hence, most biological researches are focused on the roles of proteins which are much more challenging tasks. Omics technologies, instead of analyzing individual components of an organism by conventional biochemical met...
Various mesenchymal stem cells as easily accessible and multipotent cells can share different essential signaling pathways related to their stemness ability. Understanding the mechanism of stemness ability can be useful for controlling the stem cells for regenerative medicine targets. In this context, OMICs studies can analyze the mechanism of different stem cells properties or stemness ability...
Every human being is different based on genetics, lifestyle, and environmental factors. Novel medical technologies have become more precise owing to molecular information, including genomics, transcriptomics, proteomics, metabolomics, etc. The “omics” technologies have opened up new horizons for healthcare systems, enabling them to prevent and/or diagnose diseases more precisel...
Recent advances in various 'omics' technologies enable quantitative monitoring of the abundance of various biological molecules in a high-throughput manner, and thus allow determination of their variation between different biological states on a genomic scale. Several popular 'omics' platforms that have been used in microbial systems biology include transcriptomics, which measures mRNA transcri...
type 2 diabetes mellitus (t2dm) is recognized as a public health problem and increasingly prevalent illness. key elements of the guideline for diabetes care are based on evidence-based medicine approach and apply for population, not individuals. however, individualized care can improve diabetes management. personalized medicine is otherwise called precision medicine tries to find better predict...
OMICS technologies are relatively new biomarker discovery tools that can be applied to study large sets of biological molecules. Their application in human observational studies (HOS) has become feasible in recent years due to a spectacular increase in the sensitivity, resolution and throughput of OMICS-based assays. Although, the number of OMICS techniques is ever expanding, the five most deve...
BACKGROUND 'Omics' high-throughput analyses, including genomics, epigenomics, transcriptomics, proteomics and metabolomics, are widely applied in human endometrial studies. Analysis of endometrial transcriptome patterns in physiological and pathophysiological conditions has been to date the most commonly applied 'omics' technique in human endometrium. As the technologies improve, proteomics hol...
Biomarkers are playing an increasingly important role in drug discovery and development and can be applied for many purposes, including disease mechanism study, diagnosis, prognosis, staging, and treatment selection. Advances in high-throughput “omics” technologies, including genomics, transcriptomics, proteomics and metabolomics, significantly accelerate the pace of biomarker discovery. Compre...
Traditional Chinese medicine (TCM) ZHENG is the basic concept of TCM theory. The effectiveness of TCM treatment depends on the accuracy of ZHENG differentiation. ZHENG differentiation, using the "four diagnostic methods," has the drawbacks of subjectivity and variability. Following development of omics technologies, which study the functional activities of human body from a system-wide perspect...
Objectives: Applications of OMICS to high throughput studies of changes of genes, RNAs, proteins, metabolites, and their associated functions in cells or organisms exposed to environmental chemicals has led to the emergence of a very active research field: environmental OMICS. This developing field holds an important key for improving the scientific basis for understanding the potential impacts...
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