نتایج جستجو برای: oleuropein

تعداد نتایج: 485  

2017
Wenyan Sun Bess Frost Jiankang Liu

A “Mediterranean diet” rich in plant-based foods, fish, and olive oil, is associated with reduced risk of most aging-related diseases including metabolic syndrome and neurodegenerative disorders. Oleuropein, a polyphenolic compound enriched in olive oil and leaves of the olive tree, has attracted scientific attention in recent years because of a variety of reported health benefits. While the me...

2014
Yasin Ozdemir Engin Guven Aysun Ozturk

Phenolic compounds make up 2-3% (w/w) of olive flesh, whose most abundant part is oleuropein which is responsible for the characteristic bitter taste of olive fruits. Oleuropein is a heterosidic ester of elenolic acid and hydroxytyrosol and possesses beneficial effects on human health. But most fundamental and important step of table olive processing is to reduce level of oleuropein because oli...

2017
Hassan Ahmadvand Gholamreza Shahsavari Majid Tavafi Shahrokh Bagheri Mohamad Reza Moradkhani Reza Mohammadrezaei Kkorramabadi Peyman Khosravi Maryam Jafari Khadije Zahabi Reza Eftekhar Maryam Soleimaninejad Sanaz Moghadam

BACKGROUND Oleuropein is a potent antioxidant and free-radical scavenger with antiinflammatory properties. OBJECTIVES In the present study, we evaluated the protective effects of oleuropein on myeloperoxidase (MPO) activity, nitrite, urea, creatinine and glomerulosclerosis in alloxan-induced type 1 diabetic rats. MATERIALS AND METHODS Thirty Sprague-Dawley male rats were randomly divided in...

2017
Yoko Fujiwara Chisato Tsukahara Naoe Ikeda Yasuko Sone Tomoko Ishikawa Ikuyo Ichi Taisuke Koike Yoshinori Aoki

As the beneficial effects of the Mediterranean diet on human health are well established, the phenolic compounds in olive oil have been gaining interest. Oleuropein, a major phenolic compound in olives, is known to reduce the blood glucose levels in alloxan-induced diabetic rats and rabbits, however, its effect on type 2 diabetes caused by obesity is not clear. The purpose of this study is clar...

2016
Massimo Iorizzo Silvia Jane Lombardi Vincenzo Macciola Bruno Testa Giuseppe Lustrato Francesco Lopez Antonella De Leonardis

Technological properties of two strains of Lactobacillus plantarum (B3 and B11) and one of Lactobacillus pentosus (B4), previously isolated from natural fermented green olives, have been studied in vitro. Acidifying ability, salt, temperature, and pH tolerances of all strains were found in the range reported for similar strains produced in Italy and optimal growth conditions were found to be 6....

Journal: :the iranian journal of pharmaceutical research 0
mansour esmailidehaj department of physiology, faculty of medicine, shahid sadoughi university of medical sciences, yazd, iran. seyed jalil mirhosseini cardiovascular research center, afshar hospital, shahid sadoughi university of medical sciences, yazd, iran. mohammad ebrahim rezvani department of physiology, faculty of medicine, shahid sadoughi university of medical sciences, yazd, iran. bahram rasulian razi herbal medicines research center, lorestan university of medical sciences, khorramabad, iran. mohammad hossein mosaddeghmehrjardi department of pharmacology, faculty of medicine, shahid sadoughi university of medical sciences, yazd, iran. damoon haghshenas cardiovascular research center, afshar hospital, shahid sadoughi university of medical sciences, yazd, iran.

in this study, it was surveyed to know whether an oral single dose of oleuropein could mimic the cardiac preconditioning in rats’ hearts or whether its prolonged oral administration could protect the heart against the aconitine-induced arrhythmia in rats. eighty male wistar rats were divided into two series (n = 8 in each group). in the first series, all groups (except the control (con) group) ...

2016
Babak Baharvand Mansour Esmailidehaj Jamileh Alihosaini Shirin Bajoovand Saeedeh Esmailidehaj Zeynab Hafizibarjin

BACKGROUND This study was conducted to reveal that whether i.v. injection of oleuropein, the most potent polyphenolic antioxidant in olive leaf, has any effect on the magnitude of reperfusion arrhythmia in anesthetized rats or not. METHODS Eighty male Wistar rats were divided into 8 groups of 10 each: groups 1 and 5 were assigned as the prophylactic and treatment control groups, groups 2 and ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1999
K Konno C Hirayama H Yasui M Nakamura

Leaves of the privet tree, Ligustrum obtusifolium, contain a large amount of oleuropein, a phenolic secoiridoid glycoside, which is stably kept in a compartment separate from activating enzymes. When the leaf tissue is destroyed by herbivores, enzymes localized in organelles start to activate oleuropein into a very strong protein denaturant that has protein-crosslinking and lysine-decreasing ac...

Journal: :Biochemical and biophysical research communications 2005
Hamdi K Hamdi Raquel Castellon

Oleuropein, a non-toxic secoiridoid derived from the olive tree, is a powerful antioxidant and anti-angiogenic agent. Here, we show it to be a potent anti-cancer compound, directly disrupting actin filaments in cells and in a cell-free assay. Oleuropein inhibited the proliferation and migration of advanced-grade tumor cell lines in a dose-responsive manner. In a novel tube-disruption assay, Ole...

2006
Nasir S.A. Malik Joe M. Bradford

Oleuropein is the most abundant biologically active phenolic compound in olives. It has been extensively studied for human health benefits but its role in plant development processes has received limited attention. Changes in the levels of oleuropein during early stages of flower formation and during fruit development and maturation were determined using high performance liquid chromatography. ...

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