introduction: previous studies have shown that sesame oil affects memory and learning. in the present work, effect of a diet containing 10% sesame oil used during pregnancy was evaluated on short-term passive avoidance learning of offspring rats by shuttle box. methods: female wistar rats were divided into 2 groups (n = 9 each group). control group consumed regular diet during pregnancy and the...

Background: Evidences show that parental morphine addiction impairs CNS development, learning and memory in offsprings. Since long term potentiation (LTP) is a cellular mechanism of learning and memory, in this study the effect of parental morphine addiction on LTP induction in dentate gyrus by high frequency stimulation of perforant path was assessed. Materials and methods: In this experiment...

Introduction: Evidences show that parental morphine addiction impairs CNS development, learning and memory in offsprings. Regarding the role of glutamate in dentate gyrus on learning and memory, in this study the effect of parental morphine addiction on extracellular glutamate concentration of dentate gyrus was assessed. Materials and methods: In this study 20 female and 8 male rats were addic...

Background & Aims: Apple (Malus domestica Borkh. from Rosaceae family), a rich source of phytoestrogenes has not been thoroughly tested for its reproductive effects. In this study, we investigated the effects of apple diet on rats' reproduction. Method: Nine groups of NMRI rats (n= 10 females + 2 males) with different apple diets (free- apple diet and apple diet in every other day and every tow...

The influence of extirpation of the submandibular and sublingual, parotid and all major salivary glands on pregnancy of rats was studied. The statistic analysis of the results indicated that there are statistically significant differences in the number of offsprings between before and after extirpation of the salivary glands. The parotidectomized female rats presented the smallest number of off...

Adults Charles-Foster rats were prenatally treated to phenobarbitone (10 mg/kg, i.p.) from day 13 to 21 of gestation, this being the critical period of neural development. Pregnant control rats were similarly treated with equal volume of vehicle. Adult rat offsprings at 8-9 weeks of age were subjected to open-field exploratory behaviour, elevated plus-maze and elevated zero-maze tests. The rat ...

BACKGROUND The development of insulin resistance is multifactorial, with maternal pre- and postnatal nutrition having significant influences. In this regard, high fat diet (HFD) feeding in pregnancy has been shown to increase risks of metabolic diseases. Thus, we investigated the effects of supplementation of HFD with germinated brown rice (GBR) and GBR-derived gamma oryzanol-rich extract (OE) ...

The effects of food processing and or cooking practices in the variations in morphological changes in tissues were investigated. The relationship between consumption of charred meat, which is believed to be rich in nitrosamine, by pregnant mothers and the adverse effects on the growth of their offsprings, alterations in morphology of tissues like liver and pancreas were studied. Meat was subjec...

PURPOSE To investigate the effect chronic stress in newborn rats on the progression of ligature-induced-periodontitis in adulthood. METHODS Ten couples of adult Wistar rats were selected for mating. After birth, the female and their respective offsprings were allocated into two groups. Ligature Group (LG): offsprings were only watched during breast-feeding; Stress-ligature Group (SLG): after ...