BACKGROUND Testes size is used as a proxy of male intrasexual competition, with larger testes indicative of greater competition. It has been shown that in some taxa, social mating systems reflect variance in testes size, but results are not consistent, and instead it has been suggested that genetic patterns of mating may reflect testes size. However, there are different measures of genetic patt...

Oxaliplatin (Ox) is widely used for the treatment of various tumors. Since Ox prevents DNA replication and transcription, it may affect organs with rapid cell divisions such as testes. Although its use during pregnancy has been reported, no information regarding effects on testes offspring not available yet. Thirty-two mice were randomly divided into four groups. The control group (1) was admin...

Background The objective was to determine how feeding fish oil (FO) with or without vitamin E (VITE) for mothers influences reproductive organs of male offspring at weaning. MaterialsAndMethods Sex cells as well as testes length, width and weight was lower (P

Cadmium (Cd) is a testicular toxicant and endocrine disruptor. In the present study, we investigated the effects of maternal Cd exposure during the late pregnant period on testicular development and steroidogenesis in male offspring. Pregnant mice were injected intraperitoneally with CdCl(2) (0.5mg/kg) daily from gestational day (gd) 13 to gd 17. As expected, fetal weight and crown length were ...

objective(s):the aim of this study was to evaluate the oxidative status and dna integrity in testes of wistar rat offspring exposed to omega-9 monounsaturated (mufa) at different times of late organogenesis. materials and methods:sixty female rats were divided into six groups of 10 animals. the first group served as control and received the drug vehicle, olive oil (1 ml/kg/day). the second, thi...

Existing data suggest a negative correlation between maternal sleep deprivation and male offspring reproductive capability. However, there is dearth of information on the critical period of development during which reproductive organs may be programmed. Thirty pregnant rats were divided into six groups based on the Gestation Days (GD) during which they were sleep deprived as follows: GD 17 cont...

The injection of pregnant mice with 5 mg oestradiol dipropionate induced a high proportion of bilateral cryptorchidism in the male offspring. The ectopic testes were reduced in size and occupied one of three different positions in the abdomen: pararenal, paravesicular or inguinal. The seminal vesicles were found to be similarly reduced in size whereas the adrenals and pituitaries appeared to be...

reports indicate that one of the causes of harmful to the genital system, especially the testes stress. stress could be created secondarily after some pathological conditions such as neurological diseases or environmental factors. one of the causes of stress could be scary voices, such as cat voice for mice. in this study we aimed to investigate the testes parameters in the animals that were ex...

BACKGROUND Leptin plays an important role in reproductive function, and the mechanism of this phenomenon primarily focuses on the hypothalamic-pituitary-gonadal axis. However, until now, the direct effects of leptin on the testes during development from infancy to adulthood remained unclear. The aim of the present study was to explore the effects and molecular mechanisms that underlie leptin's ...

Background Despite the bulk of studies on fatty acid supplementation in maternal diet and confirmed the positive effects on brain and vision, these effects on offspring reproductive organs have not been tested. The aim of the present study was to stereological evaluate the effect of feeding Fish Oil (FO) for mothers on the testis structure of offspring. MaterialsAndMethods Sixty mature female N...