A prospective search for gastro-oesophageal candidiasis was made by histological examination of all the biopsies taken from 465 patients endoscoped consecutively during a 12 month period. The criterion for diagnosis was the demonstration of infiltration of tissue or ulcer slough by yeasts and hyphae. Nineteen cases of candidiasis were found giving an overall incidence of 4%. There were 12 cases...

aim : the aim of this investigation is identification of candida strains isolated from patients with gastro-oesophageal candidiasis in tehran, iran.   background : gastro-oesophageal candidiasis is a rare infection and appears mainly in debilitated or immunocompromised patients. colonization by  candida spp. may occur in this region and the organism can remain for several months or years in the...

The diagnosis of gastro-oesophageal candidiasis by brush cytology was studied in two groups. In eight immunosuppressed patients clinically suspected to have candidiasis, fungal infection was confirmed on six occasions, and a diagnosis of herpetic oesophagitis was established in the other two cases. Among 482 gastric and oesophageal brushings clinically unsuspected candidiasis was found on a fur...

OBJECTIVE The therapeutic activities of cyclodextrin-associated itraconazole oral solution (itraconazole OS) by two administration routes in experimental oral and oesophageal candidiasis in mice were examined and compared. METHODS Using experimental oral and oesophageal candidiasis models in ICR mice, we investigated the efficacy of oral and intragastric administration of itraconazole OS and ...

In a prospective study of 154 AIDS patients, 48 (31%) complained of pain on swallowing both liquids and solids and 32 (21%) of these also had dysphagia. While candidiasis was the most common cause of symptoms (26 patients), discrete ulceration of the oesophagus occurred in 12 instances in 10 patients (four cytomegalovirus, four herpes simplex virus, three aphthous ulcer, one peptic ulcer). One ...

AIM The aim of this investigation is identification of Candida strains isolated from patients with gastro-oesophageal candidiasis in Tehran, Iran. BACKGROUND Gastro-oesophageal candidiasis is a rare infection and appears mainly in debilitated or immunocompromised patients. Colonization by Candida spp. may occur in this region and the organism can remain for several months or years in the abse...

Oesophageal candidiasis was diagnosed incidentally at endoscopy in two patients receiving omeprazole therapy. There were no other predisposing factors for the development of candidiasis. The infection was resolved rapidly by anti-candidal therapy and by stopping omeprazole. These findings suggest that gastric acid secretion and physiological reflux of acid into the oesophagus may play a protect...