purpose : primary localized amyloidosis of eyelid is a localized type of amyloidosis without evidence of systemic involvement, which is a quite rare clinical condition. here we report a case of primary localized amyloidosis of eyelid. case report : a 40-year-old woman presented with a four-month history of swelling of the left upper eyelid resulting in a mechanical ptosis. the mass had a firm b...

primary localized amyloidosis of eyelid is a localized type of amyloidosis without evidence of systemic involvement. we report a 75-year-old man suffering of unilateral (left) ptosis due to upper eyelid mass with bony consistency. eye examination revealed upper lid mass attached to tarsus. no ocular infection or inflammation was found. pathologist reported diffuse distribution of eosinophilic h...

A 57-year-old woman consulted our department about a plaque that had been present in her left eye for one year. Ophthalmological examination revealed a solid mass in the left conjunctival semilunar fold. An excitional biopsy was peformed, revealing an amyloid deposition. The patient was referred to the Internal Medicine Department for systemic study. All studies were negative for systemic amylo...

AMYLOIDOSIS is usually categorized as a degenerative process. Nevertheless, the nature and pathogenesis of this disorder remain most uncertain. Reimann, Koucky, and Eklund (1935) have classified amyloidosis in four groups: primary, secondary, tumour-forming, and associated with multiple myeloma. Tumour-forming amyloidosis is known to occur as a primary process in the tissues of the eye, urinary...

Abstract To present a characteristic optical coherence tomography pattern in patient with hereditary transthyretin amyloidosis ocular involvement. This is the second case reported this needle-shaped deposits on retinal surface.

Conjunctival amyloidosis is a very rare disease, and its presence may be a sign of systemic amyloidosis. We present our ocular and systemic findings in a patient with conjunctival amyloidosis. A 43-year-old man had repeated subconjunctival hemorrhages (SCHs) for two years and was referred to the Chiba University Hospital. He had comprehensive ophthalmological and systemic examinations to determ...

Background. Amyloidosis is a group of disorders characterized by deposition of an extracellular protein, known as amyloid, in an abnormal fibrillar form with highly characteristic histopathologic staining properties. The clinical presentation can vary from a focal, localized lesion where amyloidosis has minor clinical consequences to extensive systemic disease that can involve any organ system ...

PURPOSE Assessment of ocular involvement in transthyretin-related familial amyloidosis with polyneuropathy (FAP) in a large cohort of Portuguese patients. METHODS We reviewed the medical records of 513 Portuguese FAP mutation carriers, at the Ophthalmology Service, Centro Hospitalar do Porto, between 1 January 2008 and 31 January 2013. Abnormal conjunctiva vessels (ACV), Schirmer test, tear b...