LysR-type transcriptional regulators (LTTRs) compose a large family and are responsible for various physiological functions in bacteria, while little is understood about their regulatory mechanism on secondary metabolism in Streptomyces. Here we reported that StgR, a typical LTTR in Streptomyces coelicolor, was a negative regulator of undecylprodigiosin (Red) and γ-actinorhodin (Act) production...

BACKGROUND A growing body of evidence indicates that in patients after anterior cruciate ligament reconstruction (ACLR) with a combined semitendinosus and gracilis (STGR) graft there are large deficits in the internal rotation strength, which has led some authors to recommend harvest of only ST tendon whenever possible. The purpose of this study was to assess the isometric (IT) and peak torque ...

Positive feedback regulation of stgR expression for 1 secondary metabolism in Streptomyces coelicolor 2 Xu-Ming Mao, Zhi-Hao Sun, Bi-Rong Liang, Zhi-Bin Wang, Wei-Hong Feng, 3 Fang-Liang Huang and Yong-Quan Li 4 5 Zhejiang University, Institute of Biochemistry, College of Life Sciences, Hangzhou 6 310058, China 7 8 # Corresponding author: 9 E-mail: [email protected] 10 Tel: 86-571-88206632 11 Fax:...

$f(Q)$ gravity is the extension of symmetric teleparallel general relativity (STGR), in which both curvature and torsion vanish attributed to nonmetricity. This work performs theoretical analyses static spherically solutions with an anisotropic fluid for gravity. We find that off-diagonal component field equation due a coincident gauge leads stringent restrictions on functional form In addition...

We have induced with nitrosoguanidine in Streptococcus sanguis a mutation conferring inability to grow and synthesize ribonucleic acid (RNA) at 42 C, the optimal temperature for growth and RNA synthesis in the parental strain. The mutation (ts) is transferable via transforming deoxyribonucleic acid (DNA) and is replaceable by its wild-type allele with fairly high efficiency in transformation re...