The emergence or exacerbation of obsessive– compulsive (OC) symptoms during treatment with atypical antipsychotics, mostly clozapine, has been documented by numerous case reports (reviewed by Lykouras et al., 2003). In six recent reports involving nine cases, (Jonkers and deHaan, 2002; Lykouras et al., 2003) olanzapine was found either to cause de novo emergence or to exacerbate OC symptoms. In...

objective: this research aimed to study the relationship between scrupulosity and obsessivecompulsive symptoms as well as obsessive-compulsive-related cognitive styles (obsessive beliefs and thought-action fusion).  methods: this was a correlational study. the study population included all individuals who referred to counseling centers of tehran from august to december 2010 and diagnosed with o...

Treatment of obsessive-compulsive-bipolar comorbidity is relatively challenging. This case report presents the improvement of both obsessive-compulsive and mood symptoms in a female patient treated with risperidone plus valproate. Her obsessivecompulsive and manic symptoms, as assessed respectively by using The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and Young Mania Rating Scale (YMRS), ...

Objective: To explore the effect of comorbid obsessive-compulsive personality disorder (OCPD) on response inhibition functions in patients with obsessive-compulsive disorder (OCD). Methods: Forty-five obsessive-compulsive patients with obsessivecompulsive personality disorder (OCD + OCPD), 42 obsessivecompulsive patients without obsessive-compulsive personality disorder (OCD OCPD) and 54 health...

objective: the aim of the current study was to investigate the role of fusion beliefs and metacognitions in obsessive–compulsive symptoms in the general population. methods: a sample of 200 students of kharazmi university was selected from various faculties and completed the following questionnaires: metacognitions questionnaire-30 (mcq-30), thought-fusion instrument (tfi) and maudsley obsessiv...

Objective: The aim of the current study was to investigate the role of fusion beliefs and metacognitions in obsessive–compulsive symptoms in the general population. Methods: A sample of 200 students of Kharazmi University was selected from various faculties and completed the following questionnaires: Metacognitions Questionnaire-30 (MCQ-30), Thought-Fusion Instrument (TFI) and Maudsley Obses...

Advances in our understanding of the genetic and neural substrates of obsessivecompulsive disorder (OCD) and related spectrum disorders such as trichotillomania, as well as their characteristic behavioral and cognitive symptoms, render the search and evaluation of appropriate animal models especially timely. Such modeling in neurology and neuropsychiatry generally occurs on at least two levels:...

Objective: sleep disturbances are frequently undiagnosed in patients with mental disorders. the aim of the present study was to investigate the prevalence of sleep disturbances in a sample of treatment-seeking patients with obsessivecompulsive disorder (ocd). Method: a total of 123 patients were screened, of whom 63 met diagnostic criteria for ocd and were further assessed with measures of slee...

The last decade has seen a noticeable increase in the number of treatment outcome studies for pediatric obsessivecompulsive disorder (OCD). The present article describes a meta-analysis of this literature with the aim of quantifying treatment effects and examining the extent to which various patient or treatment variables are related to outcome. Results showed that pharmacotherapy with serotone...

Objective: The present study was designed to evaluate the psychometric properties of the Brazilian Portuguese version of the ObsessiveCompulsive Inventory – Revised. Method: The Obsessive-Compulsive Inventory – Revised was administered toa total of 260 participants: a clinical sample of 130 patients with anxiety disorders (64 with a diagnosis of obsessive-compulsive disorder patients, 33 diagno...