conclusions acute administration of u. dioica impairs the object-recognition task if it is used only before the training session. this may be due to its modulation on the acquisition processing of object-recognition. u. dioica has no significant effects on the consolidation or retrieval processing stages of the nor task. these results emphasize the unfavorable effect on cognitive function of pr...

potassium bromide (kbr), an old antiepileptic agent, is illegally used in pharmaceutical or food industries to improve the product appearance. kbr has been proven to influence several pathways which are important in memory formation. therefore, the present study aimed to evaluate the effect of kbr on spatial working memory using object recognition task (ort). rats received a single dose of kbr ...

Objective(s) Cannabinoids have been implicated in memory deficit. We examined the effect of AM281, cannabinoid antagonist/inverse agonist in prevention of scopolamine-induced cognitive deficit. Materials and Methods  Object recognition task was used to evaluate memory in mice. Exploration time in the first and the second trial was recorded. The differences in exploration between a previously...

abrupt cessation of morphine leads to withdrawal signs and cognitive deficits. endocannabinoid system is activated during withdrawal; therefore, the aim of the present study was to assess the effects of am281, cannabinoid antagonist/inverse agonist, on memory deficit following spontaneous morphine withdrawal. cognition was evaluated by using the object recognition task. the novel object recogni...

previous reports showed that elevated levels of glucocorticoids following morphine withdrawal play an important role in memory impairment. in addition, glucocorticoid receptor (gr) inhibitors improved memory perfor-mance in morphine withdrawal mice. since mineralocorticoid receptor (mr) and grs complement each other, the aim of the current study was to evaluate the effects of spironolactone on ...

since anethum graveolens (dill) has phytoestrogenic compounds and it is proven that estrogens exert beneficial effects on cognition; the aim of this study was to understand if this plant can improve memory performance. male balb/c mice weighing 25-30 g were used in this study and memory was assessed by the novel object recognition task. in this method, the difference in the exploration time bet...

objective(s) cannabinoids have been implicated in memory deficit. we examined the effect of am281, cannabinoid antagonist/inverse agonist in prevention of scopolamine-induced cognitive deficit. materials and methods  object recognition task was used to evaluate memory in mice. exploration time in the first and the second trial was recorded. the differences in exploration between a previously se...