Virulence characteristics of diarrheal outbreak-associated Escherichia coli O55:NM, O126:NM, and O111:NM were examined. The E. coli O55:NM strains were atypical enteropathogenic E. coli (EPEC), while the E. coli O126:NM and O111:NM strains should be classified as enteroaggregative E. coli (EAggEC). The contributions of EPEC and EAggEC to the human disease burden in Japan might be significantly ...

Enteroaggregative Escherichia coli (EAEC), which is identifined by a special characteristic “stacked brick” aggregative adherence to cultured human epithelial cells (1), has been associated with acute and persistent diarrhea in children, in food poisoning diarrhea outbreaks and in overseas travelers (2). In Japan, a massive food-borne outbreak of gastrointestinal illness caused by EAEC O untype...

The O-antigen gene clusters of Escherichia coli serogroups O117, O126, and O146 were sequenced, and 11, 10, and 11 open reading frames (ORFs) were identified, respectively. Genes required for O-antigen sugar biosynthesis, sugar transfer, and sugar processing were identified. Multiplex polymerase chain reaction (PCR) assays were developed targeting the wzx and wzy genes present in the O-antigen ...

Abstract Introduction Liver resection offers the best curative treatment for hepatic metastases secondary to colorectal (CR) cancer. The aim of this study was compare survival outcomes between patients having liver once (OR) versus those redo-liver (RR) metastases. Methods This a retrospective done on 171 who underwent (97 had OR & 74 RR) from January 2009 2020 across East Midlands hospital...

Enteroaggregative Escherichia coli (EAEC) is a newly diarrheagenic agent wherein several predominant serotypes are reported. We studied the association between those serotypes, as clonal indicators, and the trait of enteroaggregative adherence to host cells, tested by polymerase chain reaction. We also evaluated the clinical manifestations of infection in 17 hospitalized children by our most co...

BACKGROUND Enterotoxigenic Escherichia coli (ETEC) is one of the most common causes of bacterial diarrhea. Over the last decade, from 1996 to 2012, changes in the virulence antigen properties of ETEC such as heat labile (LT) and heat stable (ST) toxins, colonization factors (CFs), and 'O'-serogroups have been observed. The aim of this prospective study was to compare changes in antigenic profil...