Recent observations on conjugated proteins (l-6) raise the question as to whether the prevailing ideas concerning the nature of the attachment of nucleic acids with the proteins are valid. With certain exceptions it has generally been assumed that the nucleoproteins are salts of a polyvalent nucleic acid and a polyvalent base (protein) (7). The ideas that nucleoproteins are salt-like (polar), o...

A highly sensitive surface-enhanced Raman (SERS)-based method for detection of influenza viral nucleoproteins is described. The intrinsic SERS spectrum of the aptamer-nucleoprotein complex provides direct evidence of binding between a polyvalent anti-influenza aptamer and the nucleoproteins of three influenza strains.

Digestion of adenovirus type 2 (Ad2) or Ad5 cores with micrococcal nuclease generated four nucleoprotein species that could be resolved by electrophoresis in low-ionic-strength polyacrylamide gels: these nucleoproteins displayed mobilities equivalent to those of DNA fragments of 900 to 1,025, 775 to 850, 650 to 725, and 525 to 600 base pairs (bp) and thus were readily distinguishable from HeLa ...

This report describes a technique for the differential staining of the two types of nucleoproteins in bacteria. The staining procedure is adapted from that described by Jacobson and Webb (1952) for other cells. In several respects it is similar to techniques previously used in bacterial cytology. Visualization of the two nucleoproteins individually is possible after treatment with specific nucl...

A combination of enzymatic and staining cytological techniques with ultraviolet spectroscopy has suggested the possible participation of nucleoproteins in the synthetic processes of cells (l-4). Little is known concerning the function of enzymes in the intracellular metabolism of nucleoproteins. One approach to the problem has been through the study of the action of enzymes upon nucleoproteins....

Methods of preparation and certain properties of the "nucleoproteins" of the following organisms are described: gonococcus, meningococcus, Micrococcus catarrhalis, R pneumococcus, Streptococcus hemolyticus, Staphylococcus aureus. No essential differences between the nucleoproteins and the intact cells of gonococcus and meningococcus were observed in their ability to engender immune substances (...