نتایج جستجو برای: nucleobindin

تعداد نتایج: 97  

2012
Yuko Tagaya Aya Osaki Atsuko Miura Shuichi Okada Kihachi Ohshima Koshi Hashimoto Masanobu Yamada Tetsurou Satoh Hiroyuki Shimizu Masatomo Mori

Nucleobindin-2 is a 420 amino acid EF-hand Ca²⁺ binding protein that can be further processed to generate an 82 amino terminal peptide termed Nesfatin-1. To examine the function of secreted Nucleobindin-2 in adipocyte differentiation, cultured 3T3-L1 cells were incubated with either 0 or 100 nM of GST, GST-Nucleobindin-2, prior to and during the initiation of adipocyte differentiation. Nucleobi...

Journal: :Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2007
Yoshitaka Imura Tsuneyo Mimori

Many autoantibodies associated with nucleic acids are found in autoimmune diseases, and are important for analyzing pathophysiologic mechanisms. Toll-like receptors (TLRs) are receptor molecules for innate immunity and some of them recognize nucleic acids. Nucleic acids in autoantigens may stimulate TLR and activate antigen presenting cells as adjuvants. The Wa antigen was found as a transfer R...

Journal: :iranian red crescent medical journal 0
ayse albayrak department of infectious diseases and clinical microbiology, erzurum region education and research hospital, erzurum, turkey; department of infectious diseases and clinical microbiology, erzurum region education and research hospital, erzurum, turkey. tel: +90-4422325561, fax: +90-4422325090 ismail demiryilmaz department of general surgery, ibn-i sina hospital, turkey yavuz albayrak department of general surgery and burn unit, erzurum region education and research hospital, erzurum, turkey belkiz aylu department of general surgery and burn unit, erzurum region education and research hospital, erzurum, turkey bunyami ozogul department of general surgery and burn unit, erzurum region education and research hospital, erzurum, turkey serkan cerrah department of internal medicine, ataturk university, faculty of medicine, erzurum, turkey

results scalding was the predominant cause of burns in both categories of patients. in 19 (61.3%) burn wound infection patients, the burns were due to a scald. a significant difference was found for the nesfatin, crp, and wbc levels between the patients and the control group (p = 0.000). a significant difference was also determined between the nesfatin, crp, and wbc figures at the time of hospi...

2017
Kavishankar Gawli Naresh Ramesh Suraj Unniappan

Nucleobindin-1 has high sequence similarity to nucleobindin-2, which encodes the anorectic and metabolic peptide, nesfatin-1. We previously reported a nesfatin-1-like peptide (NLP), anorectic in fish and insulinotropic in mice islet beta-like cells. The main objective of this research was to determine whether NLP is a metabolic regulator in male Wistar rats. A single intraperitoneal (IP) inject...

2016
Lakshminarasimhan Sundarrajan Ayelén Melisa Blanco Juan Ignacio Bertucci Naresh Ramesh Luis Fabián Canosa Suraj Unniappan

Nesfatin-1 is an 82 amino acid anorexigen encoded in a secreted precursor nucleobindin-2 (NUCB2). NUCB2 was named so due to its high sequence similarity with nucleobindin-1 (NUCB1). It was recently reported that NUCB1 encodes an insulinotropic nesfatin-1-like peptide (NLP) in mice. Here, we aimed to characterize NLP in fish. RT- qPCR showed NUCB1 expression in both central and peripheral tissue...

Journal: :International Journal of Molecular Sciences 2021

Journal: :Cancer Biotherapy and Radiopharmaceuticals 2019

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