نتایج جستجو برای: nucleic acid sequence based amplification

تعداد نتایج: 3885413  

ژورنال: :مجله دانشکده پزشکی اصفهان 0
مهدی پریان دانشجوی دکتری بیوتکنولوژی پزشکی، مرکز تحقیقات بیوتکنولوژی، انستیتو پاستور ایران، تهران، ایران سمیرا محمدی یگانه دانشجوی دکتری بیوتکنولوژی پزشکی، مرکز تحقیقات بیوتکنولوژی، انستیتو پاستور ایران، تهران، ایران بهزاد خوانساری نژاد دانشجوی دکتری ویروس شناسی پزشکی، گروه میکروب شناسی و ایمنی شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی اراک، اراک، ایران مهدیه موندنی زاده دانشجوی دکتری پزشکی مولکولی، گروه ژنتیک پزشکی، دانشکده پزشکی، دانشگاه علوم پزشکی همدان، همدان، ایران

مقدمه: با توجه به محدودیت های برخی از روش های سرولوژیک در تشخیص افراد دارای عفونت با ویروس های hiv-1 و hcv، استفاده از روش های تشخیصی ملکولی در شناسایی این دو عامل اهمیت بسیار زیادی دارد. با این حال اشکال عمده ی روش های ملکولی هزینه بر بودن آن ها و نیاز به وجود دستگاه ترموسایکلرکه گران قیمت است. روش ها: این پژوهش به راه اندازی و به کارگیری یک روش nasba (nucleic acid sequence based amplification...

Journal: :The Journal of Molecular Diagnostics 2012

ژورنال: Medical Laboratory Journal 2014
Ghaffarifar, F, Jorjani, ON, Koohsar, F, Mesgarian, F, Niazi, AR, Ziaei-Hezarjaribi,, H,

Abstract Background and Objective: Culture, microscopic method is a gold standard method for identification of Lishmania parasite. The use of Molecular methods such as RT- PCR compared to microscopic methods has a higher sensitivity and specificity however, it is not widely used due to its expensive equipment and the time requested. The use of nucleic acid sequence based amplification (NASBA) ...

Journal: :archives of clinical infectious diseases 0
syed tasleem raza department of biochemistry, era’s lucknow medical college, lucknow, india; department of biochemistry, era’s lucknow medical college, lucknow, india gulraiz ali department of biochemistry, era’s lucknow medical college, lucknow, india sikandar hasan department of biochemistry, era’s lucknow medical college, lucknow, india farzana mahdi department of biochemistry, era’s lucknow medical college, lucknow, india

background nucleic acid based detection of mycobacterium tuberculosis has the potential to improve the analysis of the tuberculosis epidemiology and patient care by increasing the specificity and sensitivity of diagnosis. patients and methods fifty suspected cases were screened for m. tuberculosis by using a new primer sequence and comparing its results with the primer (is6110) most widely used...

2009

The most common direct detection methods are isolation or in-vitro cultivation, electron microscopy, immunofluorescence, immunohistochemistry, antigen enzyme-linked immunosorbent assay (antigen-ELISA), nucleic-acid hybridisation (NAH), macroand microarrays and the various techniques of nucleic acid amplification, such as the polymerase chain reaction (PCR) or the isothermal amplification method...

Journal: :iranian red crescent medical journal 0
parvin hassanzadeh department of biology, school of sciences, shiraz university, shiraz, ir iran; department of biology, school of sciences, shiraz university, shiraz, ir iran. tel/fax: +98-7112280916 jalal mardaneh department of pathobiology, school of public health and institute of public health research, tehran university of medical sciences, tehran, ir iran; alborzi clinical microbiology research center, shiraz university of medical sciences, shiraz, ir iran mohammad motamedifar department of bacteriology & virology, medical school, shiraz hiv/aids research center

conclusions nucleic acid amplification tests (naats) are very appropriate in detection of infected individuals. detection techniques such as naats are independent of bacterial viability, and have a potential to limit false negative samples, therefore, in our country, the application of different laboratory diagnosis methods including naats with culture as gold standard for determination antimic...

Journal: :Methods in molecular biology 2015
Michael G Mauk Changchun Liu Mohamed Sadik Haim H Bau

Molecular (nucleic acid)-based diagnostics tests have many advantages over immunoassays, particularly with regard to sensitivity and specificity. Most on-site diagnostic tests, however, are immunoassay-based because conventional nucleic acid-based tests (NATs) require extensive sample processing, trained operators, and specialized equipment. To make NATs more convenient, especially for point-of...

Journal: :Biochemical and Biophysical Research Communications 2004

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