the earliest evidences on circulation of avian influenza (ai) virus on the iranian poultry farms date back to 1998. great economic losses through dramatic drop in egg production and high mortality rates are characteristically attributed to h9n2 ai virus. in the present work non-structural (ns) genes of 10 iranian h9n2 chicken ai viruses collected during 1998-2007 were fully sequenced and subjec...

results no significant difference was found between the groups regarding bmht rs3797546 gene polymorphism. the c allele was not associated with ns-cl/p (or = 1.27, 95% ci = 0.85-2.79, p = 0.690). conclusions our data suggested that bmht rs3797546 gene polymorphism was not associated with risk/ protection for ns-cl/p in a sample of iranian population. larger studies are required to validate our ...

Objective(s): Neural stem/progenitor cells (NS/PCs) hold a great potential for delivery of therapeutic agents into the injured regions of the brain. Efficient gene delivery using NS/PCs may correct a genetic defect, produce therapeutic proteins or neurotransmitters, and modulate enzyme activation. Here, we investigated the efficiency of a recombinant lentivirus vector ...

BACKGROUND: The H9N2 subtype of avian influenzaviruses (AIVs) have spread in Asia and Middle East countriesand have become a serious threat to poultry industry in Iran.OBJECTIVES:Characterization of genes of H9N2 subtype involvingin pathogenicity and diagnosis are crucial in control of avianinfluenza outbreaks. The Nonstructural (NS) gene and its proteinproducts (NS1 & NS2) are important as dia...

objective: nucleostemin (ns) is a recently identified gene that is expressed mainly in the nucleoli of neuronal, embryonic and mesenchymal stem cells which plays a role in their self renewal. over expression of this gene has been reported in several cancer cell lines tumoral tissues including gastric, hepatic and prostate cancer. in this study, we investigated the effects of suppression of this...

background: the h9n2 subtype of avian influenzaviruses (aivs) have spread in asia and middle east countriesand have become a serious threat to poultry industry in iran.objectives:characterization of genes of h9n2 subtype involvingin pathogenicity and diagnosis are crucial in control of avianinfluenza outbreaks. the nonstructural (ns) gene and its proteinproducts (ns1 & ns2) are important as...

Abstract Background:   The NS (non-structural) genomic segment of influenza A virus expresses two proteins (NS1 and NS2) which are responsible for the virulence and pathogenicity of virus. In this study we investigate the characterization and variability of the NS gene recovered from H1N1 influenza viruses isolated from Iranian patients during the 2017 seasonal outbreak  and from high...

nucleostemin (ns), a stem cell-abundant nucleolar protein, is critical for maintaining the self-renewal and proliferative properties of normal and cancerous stem cells. recent data suggests that ns signaling is important for proliferation of t-cells and leukemia cells. this study was conducted to verify the role of ns in pathogenesis and treatment of t-cell acute lymphocytic leukemia (t-all). o...

In multiple sclerosis Oligodendrocytes are obliterated by the immune system. neural stem/ progenitor cells (NS/P Cs) have the capacity to differentiate into mature myelinating oligodendrocytes. In embryonic mouse cortex oligodendrocyte progenitor cells (OPCs) are more abundant than the ganglionic eminence. Doing gene set enrichment analysis using DAVID and Panther websites it was shown that Gpr...