Introduction: Recent studies have shown that intermittent normobaric hyperoxia (HO) protects the rat brain from ischemia reperfusion injury. However, the exact mechanism of this kind of protection in vivo is not known. In this study, the effect of HO on expression of TNFR1 and TNFR2 in a stroke model was investigated. Methods: In this experimental study, rats were divided into 4 groups: no...

abstract background: exercise could change the immune system. it is illustrated that abnormal environments are the primary source of physiological stresses which can disarrange the function of immune system. the purpose of this study was to investigate the effects of high volume exercise (hve) in hypoxia and normoxia conduction on the immune system response in selected inactive men. materials a...

the influence of dissolved oxygen concentration on gill histopathology of great sturgeon (huso huso) was evaluated in two weight classes (initial weight 280.9?49.2 g and 1217.9?138.1 g respectively). oxygen treatments included hypoxia (2-3 mg/l), normoxia (5-6 mg/l) and hyperoxia (9-10 mg/l). the fish were acclimated to experimental tanks for one week then randomly distributed into 9 tanks in e...

Introduction: ischemic preconditioning is one of the most important mechanisms, responsible for the increased brain resistance after stroke. One of the most important candidates to ischemia preconditioning is intermittent normobaric hyperoxia. In this study, the effect of intermittent normobaric hyperoxia on the expression of UCP2 was investigated in a stroke model. Methods: Rats were divid...

Abstract Background Hypoxia, low oxygen, is a microenvironment that promotes tumour progression, particularly in gliomas. The regulation of many biological processes are maintained by miRNAs. hypoxia status glioma cells effects the affecting expression individual miRNAs.The aims this study identifying significant miRNAs either under or overexpressed compared to normoxia and further exploring ef...

We compared in human skeletal muscle the effect of absolute vs. relative exercise intensity on AMP-activated protein kinase (AMPK) signaling and substrate metabolism under normoxic and hypoxic conditions. Eight untrained males cycled for 30 min under hypoxic conditions (11.5% O(2), 111 +/- 12 W, 72 +/- 3% hypoxia Vo(2 peak); 72% Hypoxia) or under normoxic conditions (20.9% O(2)) matched to the ...

High-intensity interval training (HIIT) is a popular method for optimising sports performance and, more recently, improving health-related parameters. The inclusion of hypoxia during HIIT can promote additional gains compared with normoxia. However, reductions in the effort intensities same performed normoxia have been reported. Studies reported that adding periods inter-effort recovery (IEH) e...

the purpose of present research was to investigate the effect of high-intensity interval exercise (hie) in hypoxia and normoxia conduction on response of serum vegf in inactive men. to this end, nine inactive young men (age 24.50±5 years, height 174.22±4/6 cm, weight 70.75±4.5 kg and maximum word output (w max) in hypoxia conduction 185±29/04 and normoxia 200.00±31/8) were selected as subjects....

We hypothesized that some of the heterogeneity of pulmonary blood flow present in the normal human lung in normoxia is due to hypoxic pulmonary vasoconstriction (HPV). If so, mild hyperoxia would decrease the heterogeneity of pulmonary perfusion, whereas it would be increased by mild hypoxia. To test this, six healthy nonsmoking subjects underwent magnetic resonance imaging (MRI) during 20 min ...