aim : the purpose of the present study was to evaluate the number and proportion of various causes of upper gastrointestinal bleeding and actual numbers of non-nsaid, non- helicobacter pylori ( h.pylori ) peptic ulcers seen in endoscopy of these patients. background : the number and the proportion of patients with non- h.pylori , non-nsaids peptic ulcer disease leading to upper gastrointestinal...

OBJECTIVE To assess the efficacy and safety of different topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) compared with oral NSAIDs and with a placebo in the treatment of chronic musculoskeletal pain.

PURPOSE A meta-analysis of randomized trials studying the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on blood pressure. DATA SOURCES AND STUDY SELECTION Eight databases were searched, yielding 38 randomized, placebo-controlled trials and 12 randomized but not placebo-controlled trials (comparing two or more NSAIDs). DATA EXTRACTION Pooled mean treatment effects were computed in...

Members of the structurally diverse class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) have the ability to prevent or reduce the occurrence of colorectal, certain other gastrointestinal, and perhaps other cancers. The antic arcinogenic property of NSAIDs has been shown in epidemiological studies with humans and in experimental carcinogenesis studies with anfinals. In addition...

Interactions between anti-inflammatory drugs and anti-diabetic drugs particularly sulphonylureas are known. Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, phenylbutazone and oxyphenbutazone are known to potentiate (I, 4, 5) and indomethacin and ibuprofen are known to antagonise the hypoglycaemic effect of oral sulphonylurea drugs (2). On the other hand Wellinger et al. (12) reporte...