In breast elastography, breast tissues usually undergo large compressions resulting in significant geometric and structural changes, and consequently nonlinear mechanical behavior. In this study, an elastography technique is presented where parameters characterizing tissue nonlinear behavior is reconstructed. Such parameters can be used for tumor tissue classification. To model the nonlinear be...

We establish the feasibility of imaging the linear and nonlinear elastic properties of soft tissue using ultrasound. We report results for breast tissue where it is conjectured that these properties may be used to discern malignant tumors from benign tumors. We consider and compare three different quantities that describe nonlinear behavior, including the variation of strain distribution with o...

A method for computing nonlinear soft–tissue deformation caused by simulated surgical procedures is presented. A mass–spring system is used to model patient individual soft–tissue. Instead of simulating dynamic behaviour, the introduced approach directly estimates the rest position of the system. Very fast and robust nonlinear soft–tissue deformation is computed using an optimization approach. ...

The development of miniaturized nonlinear optical microscopy or endoscopy is essential to complement the current imaging modalities for diagnosis and monitoring of cancers. We report on a nonlinear optical endoscope based on a double-clad photonic crystal fiber and a two-dimensional (2-D) microelectromechanical system mirror, enabling the three-dimensional (3-D) nonlinear optical imaging throug...

Elastography is developed as a quantitative approach to imaging linear elastic properties of tissues to detect suspicious tumors. In this paper a nonlinear elastography method is introduced for reconstruction of complex breast tissue properties. The elastic parameters are estimated by optimally minimizing the difference between the computed forces and experimental measures. A nonlinear adjoint ...

Introduction For preoperative surgical planning, a simulation system has to support realistic cuts, which are normally smooth and curved. Since biological soft tissue is deformed with large displacement on an incision, the soft tissue model should support nonlinearity. Although the focus of surgical planning is accuracy, good acceptance by the surgeons can only be achieved with good response ti...

Background: There is no consistent data on the mechanical properties of sheep intestine. OBJECTIVES: We performed a series of biaxial strain measurement experiments and extracted the constitutive model to describe the mechanical characteristics of the sheep intestinal tissue. METHODS: Eleven specimens were obtained freshly from sacrificed  sheep and the planar biaxial tests were performed on th...