نتایج جستجو برای: non coding rna

تعداد نتایج: 1621170  

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه تربیت مدرس - دانشکده علوم زیستی 1393

rna های غیرکدکننده شامل rna های غیرکدکننده ی بلند (long non-coding rnas) و micrornas در سال های اخیر در سرطان زایی بسیار مورد توجه قرار گرفته است. رونوشت های lncrnas از طریق دخالت در فرآیند هایی چون تنظیم پرتوانی سلول ها? تنظیم پیرایش های متناوب و سایر فرآیندهای مهم زیستی? در تنظیم پیچیدگی موجودات درگیر می باشند.احتمالا بیان lincrna-ror و واریانت های b21 وa1 با تومورزایی در ارتباط می باشند که ا...

Journal: :acta medica iranica 0
mana oloomi department of molecular biology, pasteur institute of iran, tehran, iran. najmeh yardehnavi department of molecular biology, pasteur institute of iran, tehran, iran. saeid bouzari department of molecular biology, pasteur institute of iran, tehran, iran. neda moazzezy department of molecular biology, pasteur institute of iran, tehran, iran.

breast carcinoma is the major cause of cancer-related death in women. the incidence of this carcinoma is rising and there are many attempts to decrease this problem. the aim of this study was detection of full-length cytokeratin 19 (ck19) mrna, in peripheral blood and tissue of breast cancer patients in early stage of cancer. in this study, rt-pcr (reverse transcriptase-polymerase chain reactio...

Journal: :iranian journal of basic medical sciences 0
reza sahebi department of molecular genetics, faculty of biological sciences, tarbiat modares university, tehran, iran mahshid malakootian cardiogenetic research center, rajaie cardiovascular medical and research center, iran university of medical sciences, tehran, iran baharak balalaee department of molecular genetics, faculty of biological sciences, tarbiat modares university, tehran, iran alireza shahryari stem cell research center, golestan university of medical sciences, gorgan, iran masoud khoshnia golestan research center of gastroenterology and hepatology, golestan university of medical sciences, gorgan, iran mohammad reza abbaszadegan division of human genetics, immunology research center, avicenna research institute, mashhad university of medical sciences, mashhad, iran

objective(s): similar characteristics of molecular pathways between cellular reprogramming events and tumorigenesis have been accentuated in recent years. reprogramming-related transcription factors, also known as yamanaka factors (oct4, sox2, klf4, and c-myc), are also well-known oncogenes promoting cancer initiation, progression, and cellular transformation into cancer stem cells. long non-co...

Summary: SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA associated with cancer pathogenesis. It contributes to a variety of cellular functions and recent evidence propounds its association with autophagy process. It has been showed that SOX2OT can regulate the expression of different autophagy associated factors in human cells with different mechanisms, however more remains to ...

ژورنال: علمی شیلات ایران 2022

In this study the cis and trans regulatory effect of long non-coding genes (lncRNA) on the expression of genes in fish infected by Viral hemorrhagic septicemia virus (VHS) was investigated using RNA-seq technology. At the end of experimental period (the thirty fifth day), total RNA was extracted from spleen tissue (group treated with virus) and physiological serum (control group) was used to pr...

Background:Long non-coding RNAs, as a big part of non-coding RNAs, are considered functionally more than past. These transcripts could be involved in carcinogenesis. SNHG6, as a long non-coding RNA, has been reported to be expressed more in colorectal cancer tissues than non-cancerous ones.  Colorectal cancer as a malignancy needs fast prognostic and diagnostic methods for well...

Journal: :Essays in Biochemistry 2021

Journal: :Nature Reviews Genetics 2012

Journal: :Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2020

Journal: :International Journal of Molecular Sciences 2021

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