BACKGROUND Nocardia keratitis following surgical management of penetrating corneal injury is very rare. CASE A 38-year-old male presented with a deep stromal corneal infiltration with hypopyon of 10 days duration in his left eye. He had undergone a corneal tear repair on that eye 15 days prior to the onset of keratitis. The infiltrations were along the sutured corneal tear tracts. Before pres...

Nocardia farcinica is one of the more recently identified species of the Nocardia genus. Nocardia farcinica keratitis is a rare occurrence, with only eight previously reported cases. Semi-permeable rigid contact lens use was associated with one of these reported cases. We report the first case of an extended wear soft contact lens-related Nocardia farcinica keratitis and recommend a new treatme...

We read with interest the recent article by Tendolkar et al. (5). We have been seeing and treating cases of Nocardia keratitis for a long time and have published our experiences previously (3, 4). We would like to share some of our observations on this condition for the benefit of JCM’s readers. Nocardia keratitis can occur in immunocompetent patients following minor trauma (3). While lagophtha...

1 Boiron P, Provost F, Chevier G, Dupont B. Review of nocardial infections in France 19871990. Eur J Clin Microbiol Infect Dis 1992; 11:709-14. 2 Chen CJ. Nocardia asteroides endophthalmitis. Ophdialmic Surg 1983;14:502-5. 3 Dewsnup DH, Wright DN. In vitro susceptibility of Nocardia asteroides to 25 antimicrobial agents. Anmimrob Agent Chemother 1984;25: 165-7 4 Douglas RM, Grove DI, Elliott J,...

Background & Aims: Nocardia asteroides is gram-positive, partially acid-fast, aerobic actinomycetes which cause a wide range of skin infections, and pulmonary, cerebral, and ocular infection. Case Presentation: A 60-year-old man with diabetes presented with ocular ulcers in 2015. Through the medical records evaluation, physical examination, and biochemical evaluation of the patient, Nocardia as...

INTRODUCTION Keratitis due to Nocardia infection is not commonly encountered in clinical practice and may therefore be mistaken for fungal or viral keratitis leading to delayed treatment and increased risk of permanent visual impairment. CASE An otherwise healthy 27 years old Caucasian Active Duty military member presented to the clinic with three days of light sensitivity and irritation of h...

A patient with severe non-healing microscopically proven Nocardia keratitis was treated with maximal topical amikacin followed by amniotic membrane transplantation (AMT) 2 months later (single-layer epithelial side-down). Epithelial healing was achieved, but neovascularization continued. This case report indicates that AMT combined with topical antibiotic provides pain relief and allows epithel...

Nocardia asteroides has been reported as the cause of keratitis in only 7 cases and of other ocular disease in another 12 cases. We report a case of N. asteroides keratitis that presented 3 weeks after rural trauma and progressed despite trials of appropriate antibiotics. Seven weeks after the origianl injury a successful conjunctival flap was placed over the cornea. The morphology and the sens...

PURPOSE To report the clinical, confocal scan, and histopathologic features of nocardia keratitis in a patient who developed bilateral infection following photorefractive keratectomy (PRK). CASE REPORT A 23-year-old woman underwent bilateral PRK for low myopia. On postoperative day 3, dense central stromal infiltrates were noticed in both eyes. Empirical antibiotic therapy was initiated which...

purpose: to report 3 cases of nocardia keratitis following photorefractive keratectomy (prk). report of outbreak: four eyes of 3 patients (2 female and one male) who had undergone prk by a single surgeon at a single center developed nocardia keartitis 3 to 6 weeks postoperatively. mean age was 25 (range 23-28) years and mean onset of corneal manifestations was 29 (range 21-40) days after prk. c...