conclusions nitrosamine was formed with conventional potato baking methods with the most nitrosamine formation found on the surface fried samples. nitrites amount in baked potatoes decreased. generally, the amount of nitrosamine in baked potato samples was lower than acceptable limits. results fried samples that were measured by the gas chromatography method had the highest average levels of ni...

The objectives of this project were to (1) minimize potential analytical errors caused by activated carbon (AC)-catalyzed nitrosamine formation reactions and identify the involved reaction mechanisms, and (2) evaluate the potential of AC-catalyzed nitrosamine formation under AC-based water filtration applications. The goal was to develop effective and practical strategies for the water industry...

The European Medicines Agency, the U.S. Food and Drug Administration, other regulatory agencies expect that all pharmaceutical products be assessed for potential presence of N-nitrosoamine (nitrosamine) impurities. This white paper addresses general considerations nitrosamine risk assessments oligonucleotide products. authors propose a assessment platform which should facilitate safe, consisten...

It was reported by authors that the prevalence of clinical vitamin A deficiency (VAD) has declined considerably in India, as compared to previous years [2]. However, they found a high prevalence of blood vitamin A deficiency (<20 μg/dL), a criteria for sub-clinical VAD [3]. In their data, 61% preschool children had subclinical VAD, and with this criterion, a public health problem was diagnosed ...

agricultural advancement and population growth have prompted increases in food supplies, and higher crop yields have been made possible through the application of fertilizers. large quantities of livestock and poultry on farms, along with the accumulation of biomass and agricultural residues, can cause contamination of ground water resources and other water sanitation concerns in both developin...

The influence of pasteurization and sodium chloride, sodium ascorbate, polyphosphates and sodium nitrite coupled with pasteurization on nitrosamine contents in pork was studied. Nitrosamines: dimethylonitrosamine (DMNA) and diethylonitrosamine (DENA) were extracted from raw material, distilled, condensed in an evaporator under lowered pressure and analyzed chromatographically. An inhibitory eff...

Of 38 pure cultures of microorganisms tested, only one, Pseudomonas stutzeri, was capable of forming dimethylnitrosamine from dimethylamine and nitrite during growth. Resting cells of P. stutzeri, Cryptococcus terreus, Escherichia coli, and Xanthomonas campestris formed dimethylnitrosamine, although no nitrosamine was found in growing cultures of the latter three organisms. No nitrosamine was p...

Occupational nitrosamine exposures from a rubber vehicle seal (VS) curing operation were compared with the peripheral blood lymphocyte concentrations of two nitrosamine-related DNA adducts, N(7)-methylguanine (N(7)mdG) and O(6)-methylguanine (O(6)mdG), and with the activity of the enzyme that repairs O(6)mdG adducts, O(6)-alkylguanine-DNA alkyltransferase (AGT). The occupational personal breath...

Baird, W. M.,Dipple, A.,Grover,P. L.,Sims,P. &Brookes,P. (1973) Cancer Res. 33,2386-2392 Booth, J. & Sims, P. (1974~) Biochem. Pharmacol. 23,2547-2555 Booth, J. & Sims, P. (1974b) FEBS Lett. 47,30-33 Booth, J., Keysell, G. R. & Sims, P. (1973) Biochem. Pharmacol. 22,1781-1791 Booth, J., Keysell, G. R., Pal, K. & Sims, P. (1974) FEBS Lett. 43,341-344 Boyland, E. (1950) Biochem. SOC. Symp. 5,4044...