a simple, mild and efficient method for the regioselective nitration of various aromatic compounds usingpoly(4-vinylpyridinium nitrate) (p4vpyn) in the presence of melamine trisulfonic acid (mtsa), is reported.this method provides several advantages such as good selectiveity between ortho and para positions ofaromatic compounds, clean procedure, simple work-up, short reaction times, solvent-fre...

Nitration of isoquinoline and phthalazine has been successfully demonstrated using a novel process which does not require strong acids. In this study, nitration of isoquinoline was repeated and the method applied to 1-nitroisoquinoline and the azaaromatics quinoline, quinazoline, quinoxaline and pyridine. Nitration of only quinoline was observed, with a product yield lower than that reported fo...

A simple, mild and efficient method for the regioselective nitration of various aromatic compounds usingpoly(4-vinylpyridinium nitrate) (P4VPyN) in the presence of melamine trisulfonic acid (MTSA), is reported.This method provides several advantages such as good selectiveity between ortho and para positions ofaromatic compounds, clean procedure, simple work-up, short reaction times, solvent-fre...

In this review we provide an analysis of the biochemistry of peroxynitrite and tyrosine nitration. Peroxynitrite is the product of the diffusion-controlled reaction between superoxide (O2•-) and nitric oxide (•NO). This process is in competition with the enzymatic dismutation of O2•- and the diffusion of •NO across cells and tissues and its reaction with molecular targets (e.g. guanylate cyclas...

Nitration of benzo[a]pyrene (BaP) by nitrogen dioxide (NO2) adsorbed on the surface of thermally activated coal fly ash and model aluminosilicate particles led to the formation of nitrobenzo[a]pyrenes as verified by extraction and gas chromatography/mass spectrometry (GC/MS). In situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) was utilized to follow the nitration reacti...

Nitroolefins are usually synthesized using the Henry reaction. Here we report an alternative metal-free decarboxylative nitration protocol for the preparation of the nitroolefins from α,β-unsaturated carboxylic acids using t-butylnitrite (t-BuONO) and TEMPO. α,β-Unsaturated carboxylic acids bearing β-aromatic and β-heteroaromatic substituents gave (E)-nitroolefins exclusively under mild conditi...

Inorganic nitrile halides have been studied theoretically by quantum-chemical approach and experimentally in the reactions of halogenation, nitration nitro halogenation aromatic compounds alkynes. The generation was eventually proved can be carried out using iodine system (alkali metal halides) presence alkali nitrates an acetic acid medium. It has found that reaction give products iodination, ...

Nitration of the major birch pollen allergen Bet v 1 alters the immune responses toward this protein, but the underlying chemical mechanisms are not yet understood. Here we address the efficiency and site-selectivity of the nitration reaction of recombinant protein samples of Bet v 1.0101 with different nitrating agents relevant for laboratory investigations (tetranitromethane, TNM), for physio...

 In this article, synthesis of the explosive 2, 6 (diamino) 3, 5 dinitro pyridine (ANPY) of the direct nitration reaction of 2, 6 diamino pyridine in different conditions of temperature, with density functional theory method were studied. For this purpose, at first the material contained in the both sides of reaction were geometrically optimized, then the calculation of the the...