b-carboline alkaloids such as harmaline and nicotine are naturally present in the human food chain. plants which contain b-caroline have anxiety and hallucinogenic effects. in this study the change in like – anxiety behaviors was investigated after intra- amygdala injections of nicotine and harmaline and intra action of them in male rat. different doses of harmaline, nicotine and its compounds ...

Background: There are many different kinds of cigarettes and tobacco available in the market. Since nicotine content of various brands of cigarettes are very variable, therefore evaluation and comparison of nicotine content of different brands of cigarettes is important. The goal of the present study was to determine and compare nicotine content of various domestic and imported cigarettes avail...

Repeated administration of nicotine causes incentive and behavioral sensitization in animals. Ascorbic acid administration inhibits some effects of nicotine. In the present study, the effect of ascorbic acid administration on nicotine-induced behavioral sensitization in Male Swiss-Webster mice (20-25 g) was investigated. Animals were injected with nicotine (0.25 mg/kg, i.p.) once daily for seve...

introduction: the influence of ascorbic acid on the nicotine-induced conditioned place preference (cpp) and behavioral sensitization was investigated in the present study. methods: in a pilot study, place conditioning and locomotor activity were investigated after nicotine (0.25, 0.5, 0.75, 1, 1.5 and 2 mg/kg) or ascorbic acid (1, 10, 100 and 1000 mg/kg) administration. different doses of ascor...

nicotine transdermal systems are being used as an aid to smoking cessation programs. as the kinetics of nicotine delivery is important in success of a smoking cessation program, rapid and high input of nicotine is required, which is not possible by passive methods and requires enhancement strategies such as iontophoresis. iontophoretic permeation, of nicotine looks promising, based on published...

conclusions the prevalence of nicotine use among ferdowsi university students is lower than the prevalence in the general population of iran and the prevalence in other countries. results for cigarette use, 17.6% of respondents reported using cigarettes at least once, 3.7% reported using cigarettes occasionally, and 3.9% reported using cigarettes on a regular basis. for water-pipe use, the corr...

objective(s): present study was performed in order to uncover new aspects for nicotine-induced damages on spermatogenesis cell lineage. materials and methods: for this purpose, 36 mature male wistar rats were divided into three groups as; control-sham (0.2 ml, saline normal, ip), low dose (0.2 mg/kg bw-1, ip) nicotine-received and high dose (0.4 mg/kg bw-1, ip) nicotine-received groups. followi...

objective: crocin, a carotenoid isolated from crocus sativus l. (saffron), is a pharmacologically active component of saffron. nicotine consumption can decrease fertility in males through induction of oxidative stress and dna damage. the aim of this study is to determine the effects of crocin on reproductive parameter damages in male mice exposed to nicotine. materials and methods: in this expe...

Introduction: The influence of ascorbic acid on the nicotine-induced conditioned place preference (CPP) and behavioral sensitization was investigated in the present study. Methods: In a pilot study, place conditioning and locomotor activity were investigated after nicotine (0.25, 0.5, 0.75, 1, 1.5 and 2 mg/kg) or ascorbic acid (1, 10, 100 and 1000 mg/kg) administration. Different doses of a...