BACKGROUND  Non-celiac wheat sensitivity (NCWS) is a new clinical entity in the world of  gluten-related diseases. Nickel, the most frequent cause of contact allergy, can be found in wheat  and results in systemic nickel allergy syndrome and mimics irritable bowel syndrome (IBS).  Objective: To evaluate the frequency of contact dermatitis due to nickel allergy in NCWS patients  diagnosed by a d...

CONTEXT In our Allergy Unit, we incidentally observed that a low Nickel diet, prescribed for delayed allergy to Nickel sulfate, reduced body mass index (BMI) and waist circumference in overweight patients. OBJECTIVES This pilot cross-sectional analysis was undertaken to compare the prevalence of Nickel allergy of overweight individuals versus the general population. We also had the chance to ...

Fig. 1. Allergic nickel dermatitis caused by nickel release from an electric shaver. Nickel allergy is frequent in adult Danes and dermatitis patients (1, 2). The high prevalence is mostly explained by consumer exposure to products that release nickel, e.g. watches, jewellery, buttons, zips, rivets and mobile phones (3–8). It has been debated whether classic dry electric shavers may cause nicke...

BACKGROUND To estimate the prevalence of nickel allergy, self-reports are sometimes used in epidemiological studies. Self-reports are practical and may facilitate estimation of prevalence provided that the questions are validated. OBJECTIVES To investigate the validity of self-reported nickel allergy. METHODS Three hundred and sixty-nine women, aged 30-40 years, from the general population ...

This study was performed to establish a convenient mouse model for the evaluation of nickel allergy. For sensitization, 0.2 g of nickel sulfate in petrolatum was applied 4 times every other day to the shaved dorsal skin. Seven days after the first application of the nickel sulfate salt sample, the antigen-specific metal allergy reaction was estimated based on the swelling response of the footpa...

In July 2001, the EU Nickel Directive came into full force to protect European citizens against nickel allergy and dermatitis. Prior to this intervention, Northern European governments had already begun to regulate consumer nickel exposure. According to part 2 of the EU Nickel Directive and the Danish nickel regulation, consumer items intended to be in direct and prolonged contact with the skin...

Nickel is a ubiquitous trace element and the commonest cause of metal allergy among the people. Nickel allergy is a chronic, recurring problem; females are affected more commonly than males. Nickel allergy may develop at any age. Once developed, it tends to persist life-long. Nickel is present in most of the dietary items and food is considered to be a major source of nickel exposure for the ge...

Potential relationships between the development of nickel allergy and previous ear piercing or orthodontic treatment with nickel-containing appliances were studied in 294 patients. We found 77 (31.2%) of 247 patients with pierced ears were allergic to nickel compared to only three (6.4%) patients without pierced ears (p = 0.001), which confirms earlier suggestions that nickel allergy (as assess...

Nickel allergy constitutes a serious health problem of modern societies. Hypersensitivity to this metal is found in 13% adults and 8% children. Risk factors for nickel allergy are: female gender and early exposure to nickel, e.g. piercing. Various mechanisms of inducing nickel allergy are possible, which is also reflected in the different clinical pictures. Nickel can induce allergic reaction i...

contact dermatitis is an inflammatory reaction of the skin and mucosa to either external or internal factors. it can be divided to two forms of irritant contact dermatitis and allergic contact dermatitis. nickel is one of the most common materials that causes allergic contact dermatitis and is widely used in orthodontic appliances. the inflammatory reaction to this metal in orthodontics is usua...