There is an almost dogmatic view of the different effects of moderate-level sound stimulation in neonatal vs. adult animals. It is often stated that exposure in neonates results in an expansion of the cortical area that responds to the frequencies present in the sound, being either pure tones or frequency modulated sounds. In contrast, recent findings on stimulating adult animals for a sufficie...

The effect of dehydroepiandrosterone (DHEA) on the activity and isoenzyme patterns of liver glucose 6- phosphate dehydrogenase (G6PD) was investigated in rats during different stages of growth. G6PD activity of mature rats was less than those of the immature (43%) and newborn (35%) animals. DHEA at 10 M) inhibited G6PD activity of the mature , immature and newborn rats by 79%, 39% , and 88%...

CD8(+) T cells are a major component of the adaptive response of a host to infections by viruses and other intracellular pathogenic agents. However, because of the intrinsic immaturity of the immune system of neonatal animals, neonates are highly sensitive to a variety of pathogens and may be unable to respond in a protective manner. Here we explore whether a hyperattenuated strain of Listeria ...

The physiological properties of hippocampal neurons are commonly investigated, especially because of the involvement of the hippocampus in learning and memory. Primary hippocampal cell culturing allows neuroscientists to examine the activity and properties of neurons at the individual cell and single synapse level. In this video, we will demonstrate how to isolate and grow primary hippocampal c...