the aim of this study was to determine the incidence and causes of fever as a major problem contributing to transplantation related mortality among patients undergoing hematopoietic stem cell transplantation (hsct) and evaluation of antibiotic use, according to reliable guidelines.we retrospectively reviewed hospital records of 195 adult patients who underwent hsct between 2009-2011 at hematolo...

FACTORS EFFECTIVE IN THE PROGNOSIS OF NEUTROPENIC FEVER CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA

Background: Neutropenic patients are vulnerable to a wide spectrum of infectious agents. The aim of this study was to determine the current frequency of bacterial infections in patients with nosocomial fever and neutropenia. Methods: In a retrospective study, the neutropenic patients’ specimens with nosocomial fever were cultured on blood and MacConkey agar plates and evaluated at microbiology ...

in 2004, klastersky et al. reported that fever isa common finding in patients with hematologicmalignancies, occurring in more than 80% of thepatients during or after chemotherapy.[1] he andhis colleagues also reported that the most fearedinfection in neutropenic patients is bloodstreaminfection (bsi), which significantly increases themortality rate of these patients.[2] in 2009, viscoliet al.[3...

background: neutropenic patients are vulnerable to a wide spectrum of infectious agents. the aim of this study was to determine the current frequency of bacterial infections in patients with nosocomial fever and neutropenia. methods: in a retrospective study, the neutropenic patients’ specimens with nosocomial fever were cultured on blood and macconkey agar plates and evaluated at microbiology ...

background: vancomycin is used abundantly in patients undergoing hsct, especially during neutropenic fever. despite its widespread use little is known about vancomycin pharmacokinetics in hsct patients. we conducted this study to investigate vancomycin pharmacokinetic parameters in our hsct patients and to evaluate current dosing regimen based on trough vancomycin concentrations measurement. me...

We evaluated risk factors for neutropenic fever and febrile prolonged neutropenia during vincristine-including chemotherapy to treat HIV-related lymphoma to investigate whether protease inhibitor (PI) treatment is associated with infectious complications due to drug interactions with chemotherapeutic agents. We included all HIV patients who received chemotherapy including vincristine for lympho...

Neutropenic fever is a common complication of myelosuppressive therapy in pediatric oncology patients. Piperacillin-tazobactam (PIP/TAZO) is a broad spectrum antibiotic used for empiric treatment of neutropenic fever. We describe four cases of suspected PIP/TAZO induced nephrotoxicity occurring in children with pediatric malignancies admitted to the hospital and treated for fever ± neutropenia....

OBJECTIVES The purpose of this study was to identify independent factors that can be used to predict whether febrile neutropenic patients who appear healthy at presentation will develop subsequent complications, using variables that are readily available in the emergency department (ED). METHOD The medical records of 192 episodes in which the patients presented to the ED with neutropenic feve...