objective(s): the stimulation of neural stem cells (nscs) differentiation into neurons has attracted great attention in management of neurodegenerative disease and traumatic brain injury. it has been reported that selegiline could enhance the morphologic differentiation of embryonic stem cells. therefore this study aimed to investigate the effects of selegiline on nscs differentiation with focu...

Objective(s): The stimulation of neural stem cells (NSCs) differentiation into neurons has attracted great attention in management of neurodegenerative disease and traumatic brain injury. It has been reported that selegiline could enhance the morphologic differentiation of embryonic stem cells. Therefore this study aimed to investigate the effects of selegiline on NSCs differentiation with focu...

REGULATION OF SENSORY NEURONE SURVIVAL BY NEUROTROPHIC FACTORS Neuronal death and the role of neurotrophic factors Site of neurotrophic factor synthesis Regulation of neurotrophic factor levels in the target field Stage of sensory neurone dependence on neurotrophic factors Specificity of neurotrophic factors for sensory neurones neurotrophic factors from the periphery neurotrophic factors from ...

Increasing evidence indicated astroglia-derived neurotrophic factors generation might hold a promising therapy for Parkinson's disease (PD). Resveratrol, naturally present in red wine and grapes with potential benefit for health, is well known to possess a number of pharmacological activities. Besides the antineuroinflammatory properties, we hypothesized the neuroprotective potency of resveratr...