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how to cite this article: shiari r, hassase yegane m, farivar s, javadi parvaneh v, mirjavadi sa. neuropsychiatric symptoms as the first manifestation of juvenile systemic lupus erythematosus: a complicated case with klinefelter’s syndrome. iran j child neurol. 2014 winter; 8(1):62-65. abstract systemic lupus erythematosus (sle) is an autoimmune, multisystem disorder with various manifestations...

introduction: ifosfamide (ifo) is a potent drug that is used in cancer therapy. the major uses of ifo are: solid tumors especially, osteogenic sarcoma, other soft tissue sarcomas and hematologic malignancy, especially in lymphoma patients. the toxicity of ifo is very encompassing and includes: alopecia, nausea, vomiting, gastrointestinal, renal and neurological problems. neuropsychiatric toxici...

Background: “Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections”, or PANDAS, is a syndrome characterized by acute-onset obsessive-compulsive disorder (OCD) and/or tics accompanied by the neuropsychiatric symptoms. This case is reported because of its rarity. Case report: A 6.5-year-old boy with swollen tonsils, high-grade fever and rash was admitted to Ami...

background: diagnosis and treatment of neuropsychiatric lupus is still a major challenge in clinical practice. we investigated the association between depression and anti-ribosomal p (anti-p) antibodies in a sample of iranian patients with systemic lupus erythematosus (sle). materials and methods: th is cross-sectional study was conducted on adult patients with sle referring to a referral out-p...

background: few investigations have focused on the patients with lupus nephritis (ln) and neuropsychiatric systemic lupus erythematosus (npsle). this study was aimed to investigate the clinical features, mortality, and the predictors for mortality of this group of patients. patients and methods: medical records were retrospectively reviewed in sun yat-sen memorial hospital from 1996 to 2012. da...