neuropeptides, possessing specific and functional receptors on various cells of the immune system, have the potential to regulate immune responses; and the macrophages as important components of defense against various agents, are at their influence. in this study the effect of neuropeptides substance p (sp) and calcitonin gene-related peptide (cgrp) on il-1 beta production by herpes sim¬plex t...

introduction: dental pulp has neural fibers that produce neuropeptides like substance p (sp) and calcitonin gene-related peptide (cgrp). the inflammation of dental pulp can lead to an increase amount of sp and cgrp release, especially in symptomatic irreversible pulpitis. therefore, it can be assumed that neuropeptides have some role in the progression of inflammation of the dental pulp. the ai...

We have reviewed the distribution and functions of neuropeptides in the cat hypothalamus. Our review focuses in the cat hypothalamus on the following points: 1) the distribution and coexistence of neuropeptides; 2) the anatomical relationships among the different neuropeptides; 3) the peptidergic pathways (afferences and efferences); 4) comparison of the distribution of neuropeptides in the mam...

The role of neuropeptides in modulating behavior is slowly being elucidated. With the sequencing of the C. elegans genome, the extent of the neuropeptide genes in C. elegans can be determined. To date, 113 neuropeptide genes encoding over 250 distinct neuropeptides have been identified. Of these, 40 genes encode insulin-like peptides, 31 genes encode FMRFamide-related peptides, and 42 genes enc...

6 List of original publications 7 List of abbreviations 8 1. Review of the literature 9 1.1 General aspects of neuropeptides 9 1.2 The RFamide family of neuropeptides 11 1.3 Biosynthesis and secretion of neuropeptides 13 1.4 Neuropeptide receptors 15 1.5 Functional properties of neuropeptides 17 1.5.1 Energy and fluid homeostasis 17 1.5.2 Neuropeptides and prolactin secretion 19 1.5.3 Cardiovas...