Neuropeptide Y (NPY) is an inhibitory neuromodulator expressed abundantly in the central nervous system that is suspected of being an endogenous antiepileptic agent that can control propagation of limbic seizures. Electrophysiological and pharmacological data suggest that these actions of NPY are mediated by G protein-coupled NPY Y2 and NPY Y5 receptors. To determine whether the NPY Y5 receptor...

it is known that neuropeptide y which is widely distributed throughout the central nervous system is able to prevent seizures in animals. there are limited studies about the role of neuropeptide y in febrile seizures. this study was conducted to evaluate the association between plasma neuropeptide y level and febrile seizures in children. seventy six patients with typical and atypical febrile s...

background :many pregnant muslim women choose to fast during ramadan every year worldwide. this study aimed to examine the effect of ramadan fasting on serum leptin, neuropeptide y and insulin in pregnant women and find whether fasting during pregnancy could have a negative effect on the health of mothers and fetuses.   methods : this cross-sectional study was conducted on 39 healthy volunteer ...

  Background :Many pregnant Muslim women choose to fast during Ramadan every year worldwide. This study aimed to examine the effect of Ramadan fasting on serum leptin, neuropeptide Y and insulin in pregnant women and find whether fasting during pregnancy could have a negative effect on the health of mothers and fetuses.   Methods : This cross-sectional study was conducted on 39 healthy voluntee...

2,109,698 A 3/1938 Harman ......................... 18/53 2,186,769 A 1/1940 Schirm ......... ... 260/377 4,123,530 A 10/1978 Corvi-Mora ......... ... 424/250 5,506.258 A 4/1996 Christophe et al. ......... 514/423 5,552,411 A 9/1996 Downing et al. ........... 514/312 5,554,621 A 9/1996 Poindexter et al. ......... 514/278 5,571,921 A 11/1996 Bender et al. .............. 546/199 5,602,024 A 2/199...

Different signals with key roles in energy homeostasis regulate the reproductive axis. These include neuropeptide Y and polypeptide YY(3-36), whose type Y(2) receptor is the most abundant of this family in the brain. We evaluated herein the putative roles of Y(2) receptors in the control of gonadotropin secretion by means of central administration of PYY(13-36) (agonist of Y(2) receptors) and B...

objective(s): atherosclerosis is an important risk factor for coronary heart disease. neuropeptide y (npy) and its receptors, located in peripheral tissue such as white adipose tissue, have been linked to obesity and fat storage. the role of npy in atherosclerosis has not yet been fully studied, so this study was conducted to further investigate the effect of biie 0246, an npy receptor antagoni...

Neuropeptide Y is implicated in the regulation of feeding in vertebrates, but recent studies in transgenic mice are contradictory. In this issue of Neuron, Wu et al. show a dual role for the Drosophila NPY (dNPF) in the developmental regulation of larval foraging and social behaviors, demonstrating a conserved role for this peptide in complex behaviors.

PART I CLONING TECHNIQUES 1 Cloning Neuropeptide Tyrosine cDNA Carolyn A. Worby ......................................................................... 3 2 Human Y1/Y5 Receptor Gene Cluster: Isolation and Characterization Herbert Herzog............................................................................ 13 3 HumanType 2 Neuropeptide Y Receptor Gene: Isolation and Characterization Davi...