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OBJECTIVE This case report describes the use of sacral neuromodulation to treat urinary retention after sexual abuse. METHODS Sacral neuromodulation was added to therapeutic regimen of a 38-year-old woman in whom chronic, complete urinary retention developed after psychological and sexual abuse during childhood. RESULTS The combination of psychotherapy and neuromodulation restored the patie...

Neuromodulation is central to the adaptation and robustness of animal nervous systems. This paper explores classical paradigm indirect adaptive control design neuromodulatory controllers in conductance-based neuronal models. The maximal conductance parameters shown provide a methodology aligned with concepts neuromodulation physiology impedance robotics.

In this issue of Neuromodulation, J. Van Zundert et al. have published an article titled, Percutane-ous pulsed radiofrequency treatment of the cervi-cal dorsal root ganglion in the treatment of chronic cervical pain syndromes: A clinical audit (1). The question that our readers might ask is this: Is pulsed radiofrequency neuromodulation? It is the opinion of these authors that it is. The exact ...

Neuromodulation, including invasive and non-invasive stimulation, has been used to treat intractable chronic pain. However, the mechanisms by which neuromodulation produces antinociceptive effect still remain uncertain. Optogenetic manipulation, a recently developed novel approach, has already proven its value to clinicians by providing new insights into mechanisms of current clinical neuromodu...

Objective: To report that urinary retention as a result of sexual abuse can respond to sacral neuromodulation. Method: In a 38-year-old woman in whom chronic, complete urinary retention developed as a result of psychological and sexual abuse in childhood, sacral neuromodulation was added to her therapeutic regimen in an interdisciplinary approach. Results: The combination of psychotherapy and n...

Sacral nerve stimulation, or neuromodulation, has been shown to restore voiding in women with a specific type of urinary retention that is attributed to urethral sphincter overactivity. The therapy has gained popularity in this and other voiding dysfunctions, but its mechanism of action remains unexplained. This thesis explores the effects of neuromodulation on women with urinary retention. It ...

Background: The results of existing studies regarding the use of neuromodulation in fecal incontinence (FI) are contradictory and therefore, a definitive conclusion cannot be made in this regard. Therefore, the aim of the present study is to evaluate the effectiveness of neuromodulation in controlling FI in children through a systematic review.Methods: A decision was made to perform the search ...

Ultrasound neuromodulation holds promise as a non-invasive technique for neuromodulation of the central nervous system. However, much remains to be determined about how the technique can be transformed into a useful technology, including the effect of ultrasound frequency. Previous studies have demonstrated neuromodulation in vivo using frequencies <1 MHz, with a trend toward improved efficacy ...

BACKGROUND The discovery of abnormal synchronization of neuronal activity in the basal ganglia in Parkinson's disease (PD) has prompted the development of novel neuromodulation paradigms. Coordinated reset neuromodulation intends to specifically counteract excessive synchronization and to induce cumulative unlearning of pathological synaptic connectivity and neuronal synchrony. METHODS In thi...