introduction: behcet's disease is a chronic disease with multisystem involvement characterized clinically by oral and genital aphthae, cutaneous lesions and ophthalmologic, neurologic and gastrointestinal manifestation. nervous system involvement occurs in 5.3 – 30% of patients, mostly in brain stem and basal ganglia. the common manifestations are pyramidal signs, central nervous plegia, p...

Behçet disease is a multisystem disease of unknown cause in which an inflammatory perivasculitis can arise in almost any tissue (Sakane et al., 1999). Neurologic involvement in Behçet disease was first reported by Knapp in 1941. It represented between 4-49% of manifestations of BD (Haghighi et al., 2005). There is one of the most serious causes of long term morbidity and mortality in Behçet’s D...

Background Behcet’s disease (BD) is a multisystemic of unknown cause. Anti-Mullerian hormone (AMH) one the key parameters for assessing reproductive function and ovarian reserve. The levels AMH correlates with residual follicular pool in women age. Objectives To assess BD female patients child-bearing potential, analyze relationship between severity, as well serum different therapeutic regimens...

Background: The use and benefit of biologic targeted therapy in the treatment refractory manifestations behcet’s syndrome remain unclearly defined due to relative paucity published research. Neuro-behcet’s disease represents a challenging clinical presentation. lack identified effective strategies management neuro-behcet’s adds burden contributes tight control. [1-3] Objectives: aim this system...

Background: Behçet disease (BD) is a systemic and potentially severe disease. Its incidence varies widely worldwide. In Spain, published BD’s epidemiological studies are scarce. Objectives: well-defined Northern Spanish population-based cohort, the aim of this study was ) to estimate variations, b clinical domains c compare our results with other regions. Methods: Study unselected all consecuti...