BACKGROUND National data suggest widespread gestational exposure to organophosphate pesticides (OPs) based on the detection of OP metabolites in the urine of pregnant women. Associations with early infant neurobehavior are largely understudied, with only two studies reporting abnormal reflexes in newborns in association with gestational exposure to OPs. Our objective was to utilize biological m...

Maternal nutrition plays a critical role in physical growth and neurobehavior of offspring. The aim of this study was to assess the nature of maternal undernutrition on the physical growth and neurobehavior of newborn male and female rat pups. To attain this aim, a model of maternal 50% food restriction (FR50) was induced in Wistar rats. After parturition, the physical growth and neurobehavior ...

OBJECTIVE To study the effect of oil massage on growth and neurobehavior in preterm babies less than 1500 g. DESIGN Randomized Controlled Trial. SETTING Tertiary level neonatal unit of a teaching hospital. SUBJECTS Neonates with birth weight <1500 grams, gestation >37 weeks, receiving enteral feeds of at least 100 mL/kg/day and less than 10 days of age. OUTCOME VARIABLES Primary-Weight ...

Advances in the developmental origins of chronic diseases suggest that there are multiple environmental influences linked to normal variations in fetoplacental development [1]. The mechanism of this plasticity is thought to be through fetal programming involving epigenetic processes that alter gene expression and permanently set pathways linked to disease. A key question in the burgeoning field...

PURPOSE The purpose of this study was to test the psychometric properties of the Neurobehavior Inventory (NBI) in a group of temporal lobe epilepsy (TLE) patients from a tertiary care center, correlating its scores with the presence of psychiatric symptoms. METHODS Clinical and sociodemographic data from ninety-six TLE outpatients were collected, and a neuropsychiatric evaluation was performe...

Epidemiological studies have revealed that radiation causes brain development abnormalities in atomic bomb survivors exposed in utero. Rat and mouse studies have also shown that prenatal exposure to low-linear energy transfer radiation induces developmental brain anomalies. Because the effects of prenatal irradiation on adult behavior patterns remain largely unknown, the present study investiga...

Methylmercury (MeHg) is a ubiquitous environmental neurotoxicant, with human exposures predominantly resulting from fish consumption. Developmental exposure of zebrafish to MeHg is known to alter their neurobehavior. The current study investigated the direct exposure and transgenerational effects of MeHg, at tissue doses similar to those detected in exposed human populations, on sperm epimutati...

OBJECTIVE To examine the relation between the neurobehavior of very preterm infants and the level of NICU quality of developmental care. METHODS The neurobehavior of 178 very preterm infants (gestational age ≤29 weeks and/or birth weight ≤1500 g) from 25 NICUs participating in a large multicenter, longitudinal study (Neonatal Adequate Care for Quality of Life, NEO-ACQUA) was examined with a s...

BACKGROUND Bisphenol A (BPA) has been shown to affect brain and behavior in rodents and nonhuman primates, but there are few studies focusing on its relationship to human neurobehavior. We aimed to investigate the relationship between environmental exposure to BPA and childhood neurobehavior. METHODS Urinary BPA concentrations and behavioral and learning characteristics were assessed in a gen...