Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen antibodies through the placenta. At the moment of the diagnosis, the mothers are asymptomatic in 40 to 60% of cases. The most common manifestations are cutaneous lesions and congenital heart block. The cutaneous findings are variable and usually begin ...

Background:Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organ involvement and periods of relapse and remission that mainly affects young women of childbearing age. In this regard the reproductive health is an important issue. Although diagnosis, treatment and management of pregnancy in SLE women have been improved recently, but the main concern is effects of SLE on ...

Two children with lupus erythematosus and myelopathy were studied. The first child developed the neonatal lupus erythematosus syndrome associated with transplacentally acquired anti-Ro/SSA antibodies. The cutaneous manifestations of neonatal lupus erythematosus disappeared but a residual myelopathy was confirmed at 16 months of age. The second child developed cutaneous lupus erythematosus at 3 ...

Neonatal Lupus Erythematosus (NLE) is a rare disease associated with placental transport of maternal anti-Ro/La and/or anti-U1RNP antibodies into the fetal circulation and characterized by cardiac, cutaneous, hematologic and hepatic manifestations. The most serious complication of NLE is complete heart block and cardiomyopathy. The maternal connective tissue disorder has been systemic lupus ery...

Neonatal lupus erythematosus is an uncommon transplacentally acquired autoimmune disorder. The most common clinical manifestations are skin rash, congenital atrioventricular block, thrombocytopenia, leukopenia, anemia, and hepatosplenomegaly. Usually, the skin rash resembles subacute cutaneous lupus, but different forms of rash have been reported in neonatal lupus erythematosus and some are rar...

Neonatal lupus erythematosus is a very rare disease, clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart block. Generally, when patients have skin manifestations, they have no cardiac defects and vice-versa; however, in 10% of cases these manifestations may coexist. Other findings may include hematologic, hepatic and ne...

background: neonatal lupus erythematosus is an uncommon disease. congenital complete heart block (cchb) usually happens in neonates with maternal systemic lupus erythematosus. the most prevalent presentation of cchbis bradycardiathatcanbediagnosed through an electrocardiogram. case report: here in, we present the case of a full-term male neonate with gestational age of 37 weeks and birth weight...

Neonatal lupus erythematosus is an autoimmune disorder mainly affecting the heart and skin. It is the most common cause of congenital heart block. In addition, hematological, hepatobiliary and neurological involvement may occur. Herein, we report a 23-day-old infant presented with annular, erythematous, and scaly and atrophic lesions on the face and trunk. Based on the clinical, laboratory and ...

Neonatal lupus erythematosus (NLE) is a rare autoimmune condition caused by transplacental passage of maternal IgG autoantibodies to the fetus. It often presents with erythematous annular lesions on scalp and periorbital area that appear after exposure sunlight. Clinicians should be aware broad manifestations neonatal erythematosus, including cutaneous, cardiac, hematologic, hepatic neurologica...