PURPOSE To evaluate the clinical features, associated factors, and treatment outcomes of scleritis in the Korean population. METHODS Medical records were retrospectively reviewed for 94 eyes of 76 patients with scleritis. Clinical features of scleritis, including systemic disease, presence of microorganisms, serologic markers, history of previous ocular surgery, and use of immunosuppressants ...

Necrotizing scleritis is the most severe form of scleritis with a significant threat to vision and globe integrity. It can be infectious, surgically induced necrotizing scleritis (SINS) or systemic autoimmune associated. We report a case of necrotizing scleritis associated with 5-fluorouracil (5-FU) at the site of sub tenon’s block in a patient with previous trabeculectomy. To our knowledge, th...

purpose: to report a case of eviceration because of necrotizing scletitis 3 years after ptrygium surgery with mitomycin c. patient and findings: a 62-year-old diabetic woman with history of bilateral ptrygium surgery with mmc 3 years ago, was referred due to severe pain in her right eye. visual acuity was counting fingers at 2 m. there was thinning and melting of the sclera with uveal prolapse ...

The authors present a case of necrotizing scleritis after pterygium excision successfully treated with rituximab after attempts with high doses of corticosteroids and immunosuppressive drugs. A literature review revealed case reports and a phase I/II dose-ranging randomized clinical trial using rituximab for necrotizing scleritis with or without association with autoimmune disease. This is the ...

Scleritis is a severe painful inflammatory process centred in the sclera. A scleritis may be a harbinger of many systemic diseases so that it is important to exclude multisystem disease. We describe a case of unilateral tubercular anterior nodular non-necrotizing scleritis. Anterior nodular non-necrotizing scleritis is relatively an uncommon manifestation of tuberculosis. It may be difficult to...

Purpose In this report we record the first surgically induced Necrotizing Scleritis case related to trabeculectomy with the use of Ologen Collagen Matrix Implant. Observations Surgically induced Necrotizing Scleritis is a rare pathological entity that complicates ocular (sclera) surgery. Conclusions and importance Prompt management of surgically induced Necrotizing Scleritis related to trab...

PURPOSE To report a case of peripheral ulcerative keratitis and necrotizing scleritis precipitated by trauma in a patient with mixed cryoglobulinemia due to hepatitis C viral infection. METHODS Case report and literature review. RESULTS A 62-year-old man with a history of mixed cryoglobulinemia developed an episode of necrotizing scleritis and peripheral ulcerative keratitis one month after...

PURPOSE The purpose of this study was to review the clinical experiences of scleritis and episcleritis in Southern Taiwanese people during a 7-year period. METHODS The charts of 89 patients (representing 101 eyes) who had visited our clinic from January 2003 to July 2010 were retrospectively reviewed. They were diagnosed as having episcleritis or scleritis. The medical charts, slit lamp photo...

Scleritis is a severe inflammatory disease characterized by edema and inflammatory cell infiltration of the sclera [1, 2]. Without treatment, the condition may be progressively destructive, leading sometimes to loss of vision or loss of the eye [1, 2]. About 30–50% of all scleritis patients have an associated systemic disease [1]. Most common associations are: rheumatoid arthritis (50–60%) and ...

Necrotizing scleritis is the most severe and destructive form of scleritis with vision-threatening sequelae. It is divided into with inflammation and without inflammation (scleromalacia perforans). Adalimumab is a tumour necrosis factor (TNF)-inhibiting anti-inflammatory medication licensed for the treatment of rheumatoid and psoriatic arthritis, ankylosing spondylitis and inflammatory bowel di...