background: although lowering of food cholesterol is an effective way to reduce blood cholesterol, but recently some effective health and bioactivity characteristics of the milk fat components have been identified, so by decreasing the use of milk fat, an important source of fat-soluble vitamins and bioactive components of milk is limited. recent studies have shown that the growth of lactic aci...

Objective(s): Several beneficial effects have been attributed to the probiotic lactic acid bacteria. It was determined that lactobacilli can exert antiproliferative effects on the various cancer cell lines including colon cancer. Effects of lactic acid bacteria on colon cancer may vary from strain to strain and there is a need to find the new probiotic strains with tumor suppressing properties ...

objective(s): several beneficial effects have been attributed to the probiotic lactic acid bacteria. it was determined that lactobacilli can exert antiproliferative effects on the various cancer cell lines including colon cancer. effects of lactic acid bacteria on colon cancer may vary from strain to strain and there is a need to find the new probiotic strains with tumor suppressing properties ...

OBJECTIVES Several beneficial effects have been attributed to the probiotic lactic acid bacteria. It was determined that lactobacilli can exert antiproliferative effects on the various cancer cell lines including colon cancer. Effects of lactic acid bacteria on colon cancer may vary from strain to strain and there is a need to find the new probiotic strains with tumor suppressing properties thr...

This study aimed at applying both growth and survival approaches to compare three native strains of lactobacilli, belonging to Lactobacillus plantarum, Lactobacillus rhamnosus and Lactobacillus acidophilus species, with two commercial probiotic strains in their tolerance to acid and bile. The association between the data obtained from the methods was studied.  The results of the different metho...

this study aimed at applying both growth and survival approaches to compare three native strains of lactobacilli, belonging to lactobacillus plantarum, lactobacillus rhamnosus and lactobacillus acidophilus species, with two commercial probiotic strains in their tolerance to acid and bile. the association between the data obtained from the methods was studied.  the results of the different metho...

objective: irinotecan is a botanical derivative and an anti-cancer drug with cytotoxic and genotoxic effects. the present study evaluated the effect of lactobacillus plantarum a7 on the genotoxic activity of irinotecan in a hepatocellular carcinoma cell line (hepg2) by comet assay. materials and methods: hepg2 were incubated with irinotecan (100 µm), heat-killed cells (0.025 µg/ml) + irinotecan...

Objective: Irinotecan is a botanical derivative and an anti-cancer drug with cytotoxic and genotoxic effects. The present study evaluated the effect of Lactobacillus plantarum A7 on the genotoxic activity of irinotecan in a hepatocellular carcinoma cell line (HepG2) by comet assay. Materials and Methods: HepG2 were incubated with irinotecan (100 µM), heat-killed cells (0.025 µg/ml) + irinotecan...

background: based on literature, in vitro cholesterol removal of lactic acid bacteria has been accounted for their in vivo cholesterol reduction. but recently, it has been proposed that such in vitro characteristic may not be directly relevant to their in vivo activity. the objective of this study was to find how much in vitro cholesterol reducing potential of lactobacillus plantarum a7 (la7), ...

OBJECTIVE Irinotecan is a botanical derivative and an anti-cancer drug with cytotoxic and genotoxic effects. The present study evaluated the effect of Lactobacillus plantarum A7 on the genotoxic activity of irinotecan in a hepatocellular carcinoma cell line (HepG2) by comet assay. MATERIALS AND METHODS HepG2 were incubated with irinotecan (100 µM), heat-killed cells (0.025 µg/ml) + irinotecan...