objective(s):investigation of phase diagram of various drug formulations is effective to predict different phase region of drugs to detect final formula. the purpose of this research was to develop the ternary phase diagrams for a drug microemulsion system consisting of cucurbita pepo (pumpkin) oil, surfactant (tween 80) and deionized water. materials and methods:an electrical conductivity was ...

Celecoxib, a selective cyclo-oxygenase – 2 inhibitor has been recommended orally for the treatment of arthritis and osteoarthritis. Long term oral administration of celecoxib produces serious gastrointestinal side effects. Therefore the aim of the present investigation was to assess the potential of nanosized emulsion formulations for transdermal delivery of celecoxib (CXB), to reduce the side ...

We have studied thermodynamics of vapor nucleation on a spherical wettable dielectric nanoparticle carrying a discrete electric charge located at a certain distance from the particle center. New general equations for the chemical potential of a condensate molecule in the droplet around the particle, the work of the droplet formation and the droplet shape as functions of the effective radius of ...

We have measured the contact angle of microsized and nanosized alkane droplets partially wetting a model substrate using true noncontact atomic force microscopy. The large range of droplet sizes accessible using this technique allowed us to determine the contact line curvature dependence of the contact angle with unprecedented accuracy. Whereas previous studies aimed at explaining such a depend...

Oil and water do not mix, but often they are made to mix in the form of emulsions by dispersing either component as fine droplets in the other. Emulsions are widely used in such industries as food, pharmaceutical, cosmetic, chemical, agricultural, print/ink, and petroleum. In recent years, considerable interest has emerged in emulsions containing droplets in the size range between 20 nm and 200...

Bioactive essential oil components, aldehydes, terpenes and phenols can be encapsulated into nanosized emulsified droplets. Nano-encapsulated bioactive oils emulsions were prepared by high amplitude ultrasonic homogenization with food grade ingredients. The effect of delivery system on the antimicrobial activity of different oils components, e.g., carvacrol, lemon grass and cinnamaldehyde, was ...

We use molecular dynamics simulations to study the evaporation of particle-laden droplets on a heated surface. The droplets are composed of a Lennard-Jones fluid containing rigid particles, which are spherical sections of an atomic lattice, and heating is controlled through the temperature of an atomistic substrate. We observe that sufficiently large (but still nanosized) particle-laden drops e...

background: in the recent years nanostructured materials have been the focus of researches due to their wide-spread possibilities to provide new shapes and structures for some materials. microemulsions can provide uniform nano-sized droplets for templating. microemulsions are isotropic, thermodynamically-stable systems of oil, water and surfactant with a 20-200 nm droplet size. they can be prep...

nanosized al2o3 powder is synthesized by thermal metal organic chemical vapor deposition (mocvd)combined withplasma. the effects of reaction temperature, pressure, al(ch3)3 (tma) concentration and reactant gases (co2 and o2) on the characteristics of the synthesized al2o3 powders are investigated. the experimental results demonstrate that very fineal2o3 powders with mean particle size of about ...