BACKGROUND Although opioids suppressive effects on immune system function have been reported, this study demonstrates inflammatory reactions, such as production of pro-inflammatory cytokines and suppression of anti-inflammatory cytokines, are the main causes at organ's allotransplantation rejection in chronic morphine-treated recipients. METHODS 28 rats were categorized in 4 groups through in...

BACKGROUND Punica granatum Linn. (PG) is native to the Mediterranean region. Its flower exhibited antioxidant activity. The present study attempt to investigate the effect of these extract on uterine contraction and its possible mechanism(s). METHODS Thirty five female Wistar rats (200-300 g) at estrous phases of cycle was examined in this study; pieces of virgin adult rat uterus (1.5 cm) wer...

this study investigated the anticonvulsant activity and possible mechanism of action of an aqueous solution of dorema ammoniacum gum (dag) which has been used traditionally in the treatment of convulsions.in this study, the anticonvulsant activity of dag was examined using the pentylentetrazole (ptz) model in mice. thirty male albino mice were divided randomly and equally to 5 groups, and pretr...

background: although opioids suppressive effects on immune system function have been reported, this study demonstrates inflammatory reactions, such as production of pro-inflammatory cytokines and suppression of anti-inflammatory cytokines, are the main causes at organ’s allotransplantation rejection in chronic morphine-treated recipients. methods: 28 rats were categorized in 4groups through int...

background: punica granatum linn. (pg) is native to the mediterranean region. its flower exhibited antioxidant activity. the present study attempt to investigate the effect of these extract on uterine contraction and its possible mechanism(s). methods: thirty five female wistar rats (200-300 g) at estrous phases of cycle was examined in this study; pieces of virgin adult rat uterus (1.5 cm) wer...

Background: Although opioids suppressive effects on immune system function have been reported, this study demonstrates inflammatory reactions, such as production of pro-inflammatory cytokines and suppression of anti-inflammatory cytokines, are the main causes at organ’s allotransplantation rejection in chronic morphine-treated recipients. Methods: 28 rats were categorized in 4groups through int...

The role of opioid receptor and voltage dependent calcium channels on the kindling induced by the convulsant pentylenetetrazole (PTZ) were investigated in the rats. Experiment involved 24 rats which were divided into four groups. Kindling was established with PTZ in subconvulsive dose (37.5 mg/kg i.p.) every 48 h and effects were observed within 20 min using five-point scoring system. All anima...

The effects of aqueous and ethanolic leaf extracts of Mentha Longifolia on morphine dependence were examined in mice. Dependence was induced using subcutaneous injections of morphine daily for 3 days. On day 4, the last dose of morphine was injected 2 h perior the intraperitoneal injection of naloxone. The number of episods of jumping during 30 minutes after injection of naloxane was considered...

herbal medicine has an old history with a broad application all over the world. many researches have focused on the curative as well as antinociceptive effects of herbal extract. the aim of this study was to investigate the analgesic effects of berberis vulgaris hydroethanolic extract (bve) in male mice. 30 male mice were divided into 5 groups: control, treated by morphine, treated by bve (150 ...

Herbal medicine has an old history with a broad application all over the world. Many researches have focused on the curative as well as antinociceptive effects of herbal extract. The aim of this study was to investigate the analgesic effects of Berberis vulgaris hydroethanolic extract (BVE) in male mice. 30 male mice were divided into 5 groups: control, treated by morphine, treated by ...