OBJECTIVES Autoimmune hepatitis (AIH) is a relatively rare cause of hepatic dysfunction, which can lead to acute liver failure (ALV) and cirrhosis if not treated. The performance of transient elastography (TE) compared to liver biopsy has been evaluated in many liver diseases. The aim of the present study was to evaluate the performance of TE and other non-invasive markers for liver fiibrosis i...

methods fifty-three patients who were treated at the department of gastroenterology and hepatology of the university clinic essen from 2008 to 2013 included in this retrospective study. laboratory parameters were used to calculate non-invasive markers for liver fiibrosis. every patient underwent a liver biopsy within 6 months of the liver stiffness measurement. objectives autoimmune hepatitis (...

OBJECTIVE This study was designed to compare the association between the body mass index (BMI) and symptoms of gastroesophageal reflux disease (GERD) in allegedly normal subjects undergoing regular medical checkups and subjects diagnosed with non-alcoholic fatty liver disease (NAFLD). Additionally, the correlation between the BMI and GERD symptoms was evaluated in subjects with NAFLD. METHODS...

Background. Nonalcoholic fatty liver disease (NAFLD) is one of the metabolic disorders presented in liver. The relationship between severity of NAFLD and coronary atherosclerotic burden remains largely unknown. Methods and Materials. We analyzed subjects undergoing coronary calcium score evaluation by computed tomography (MDCT) and fatty liver assessment using abdominal ultrasonography. Framing...

Intestinal FGF19 has emerged as a novel endocrine regulator of hepatic bile salt and lipid metabolism. In patients with nonalcoholic fatty liver disease (NAFLD) hepatic lipid metabolism is deranged. A possible role of FGF19 in NAFLD has not been reported yet. In this study, we assessed intestinal FGF19 production and the hepatic response to FGF19 in NAFLD patients with and without insulin resis...

30 Intestinal FGF19 has emerged as a novel endocrine regulator of hepatic bile salt and lipid 31 metabolism. In patients with non-alcoholic fatty liver disease (NAFLD) hepatic lipid 32 metabolism is deranged. A possible role of FGF19 in NAFLD has not been reported yet. In this 33 study, we assessed intestinal FGF19 production and the hepatic response to FGF19 in NAFLD 34 patients with and witho...

OBJECTIVES Presence of non-alcoholic fatty liver disease (NAFLD) can predict risks for diabetes, cardiovascular disease and advanced liver disease in the general population. We aimed to establish a non-invasive score for prediction of NAFLD in Han Chinese, the largest ethnic group in the world, and detect whether ethnicity influences the accuracy of such a score. METHODS Liver fat content (LF...

Considering limitations of liver biopsy for diagnosis of nonalcoholic liver disease (NAFLD), biomarkers' panels were proposed. The aims of this study were to establish models based on serum adipokines for discriminating NAFLD from healthy individuals and nonalcoholic steatohepatitis (NASH) from simple steatosis.This case-control study was conducted in patients with persistent elevated serum ami...

OBJECTIVE The relation between childhood overweight and adult non-alcoholic fatty liver disease (NAFLD) is largely unknown. We investigated if weight and weight gain in childhood increases the risk of being diagnosed with NAFLD in routine clinical settings in adulthood. PARTICIPANTS We studied 244,464 boys and girls, born between 1930 and 1989, who attended school in Copenhagen, Denmark. Thei...

1162 NAFLD Diagnostic performance of FibroTest, SteatoTest, and ActiTest in patients with NAFLD using the SAF-score as histological reference M Munteanu, D Tiniakos, Q Anstee, F Charlotte, G Marchesini, E Bugianesi, MH. Trauner, CP. Oliveira, C Day, JF Dufour, S Bellentani, Y Ngo, S Traussnigg, P Bedossa, V Ratziu, T Poynard. The study aimed to improve the validation of three blood tests used i...