The splicing of the N exon in the pre-mRNA coding for the RE1-silencing transcription factor (REST) results in a truncated protein that modifies the expression pattern of some of its target genes. A weak 3'ss, three alternative 5'ss (N4-, N50-, and N62-5'ss) and a variety of putative target sites for splicing regulatory proteins are found around the N exon; two GGGG codes (G2-G3) and a poly-Uri...

We present results of six-dimensional ~6D! quantum wave-packet calculations for the dissociative adsorption of (n50,j54,m j) H2 on Cu~100!. The potential-energy surface is a fit to points calculated using density-functional theory ~DFT!, with the generalized gradient approximation ~GGA!, and a slab representation for the surface. New aspects of the methodology we use to adapt the wave function ...

Assembly and super scaffolding with multiple genera. We examined experiments from 16 different genera to determine if the results seen for the Tribolium castaneum genome are typical for other genomes as well. The T. castaneum genome map N50 was found to be in the high end of the probability density distribution (Additional file 6; Figure 1). The same is true for the Tcas5.0 draft sequence assem...

An autumn-winter trial was carried out in Southern Italy open-field conditions on butterhead lettuce to investigate the effect of nitrogen (N) fertilizer rate (0, 50, and 100 kg ha−1, N0, N50, N100) application azoxystrobin, sprayed twice an earlier vs. a later scheme, specifically at 65/85 or 65/100 days after transplantation. untreated control also included. The evaluation product quality con...

Abstract. A global model perturbed parameter ensemble of 60 simulations was used to explore how combinations six parameters related secondary organic aerosol (SOA) formation affect particle number concentrations and mass. The represent the compounds with different volatilities from biogenic anthropogenic sources. most plausible were determined by comparing against observations concentration par...

The 22-gigabase genome of loblolly pine (Pinus taeda) is one of the largest ever sequenced. The draft assembly published in 2014 was built entirely from short Illumina reads, with lengths ranging from 100 to 250 base pairs (bp). The assembly was quite fragmented, containing over 11 million contigs whose weighted average (N50) size was 8206 bp. To improve this result, we generated approximately ...

Results are presented of calculations on the experimentally observed lifetime enhancement of high principal quantum number n f (N52) and np(N50) Rydberg states of the NO molecule in small dc electric fields. A Hund’s case (d) molecular Hamiltonian is introduced, which describes intramolecular interactions between low angular momentum Rydberg states as a result of core penetration and l mixing c...