نتایج جستجو برای: mutations

تعداد نتایج: 172787  

2002
Alexis Hernández

We study compact non-supersymmetric Z N orbifolds in various dimensions. We compute the spectrum of several tachyonic type II and heterotic examples and partially classify tachyon-free heterotic models. We also discuss the relation to compactification on K3 and Calabi-Yau manifolds.

Journal: :hepatitis monthly 0
reza rezaee ministry of health and medical education, deputy of curative affairs, budget administration, tehran, ir iran mansour poorebrahim department of medical biotechnology, school of advanced technologies in medicine, tehran university of medical sciences, tehran, ir iran saeideh najafi department of microbiology, tonekabon branch, islamic azad university, tonekabon, mazandaran, ir iran solmaz sadeghi department of medical biotechnology, school of advanced technologies in medicine, tehran university of medical sciences, tehran, ir iran alieh pourdast department of infectious diseases, imam khomeini hospital complex, tehran university of medical sciences, tehran, ir iran seyed moayed alavian middle east liver diseases (meld) center, tehran, ir iran; baqiyatallah research center for gastroenterology and liver diseases, baqiyatallah university of medical sciences, tehran, ir iran

conclusions these data will be beneficial for designing more advanced antibodies for the recognition of the hbsag in diagnostics. in addition, the results of this study may assist in the design or development of more effective hepatitis b vaccines. results the g145r mutation causes a considerable reduction in the immunogenic activity of the hbsag through a conformational change in the hbsag ant...

Journal: :medical laboratory journal 0
farzane salarneia golestan university of medical sciences, gorgan, iran sare zhand golestan university of medical sciences, gorgan, iran behnaz khodabakhshi golestan university of medical sciences, gorgan, iran alijan tabarraei golestan university of medical sciences, gorgan, iran mohammad ali vakili golestan university of medical sciences, gorgan, iran naeme javid golestan university of medical sciences, gorgan, iran

abstract       background and objective: hepatitis b virus (hbv) is a dna virus with high tendency toward hepatic tissue. there are currently about 3 million hbv-infected people and 350 to 400 million chronic carriers of this virus in the world. x protein plays a role in the over-expression of oncogenes, carcinogenicity of liver cells and overlaps with the basal core promoter of the virus. muta...

2003
ANDRE HENRIQUES

It is well-known that an effective orbifold M (one for which the local stabilizer groups act effectively) can be presented as a quotient of a smooth manifold P by a locally free action of a compact lie group K. We use the language of groupoids to provide a partial answer to the question of whether a noneffective orbifold can be so presented. We also note some connections to stacks and gerbes.

2008
Takeshi Araki Tatsuo Kobayashi Jisuke Kubo Saúl Ramos-Sánchez Michael Ratz Patrick K.S. Vaudrevange

We derive anomaly constraints for Abelian and non-Abelian discrete symmetries using the path integral approach. We survey anomalies of discrete symmetries in heterotic orbifolds and find a new relation between such anomalies and the socalled ‘anomalous’ U(1).

1998
B. R. Greene C. I. Lazaroiu Piljin Yi

We formulate the effective field theory of a D-particle on orbifolds of T 4 by a cyclic group as a gauge theory in a V -bundle over the dual orbifold. We argue that this theory admits Fayet-Iliopoulos terms analogous to those present in the case of noncompact orbifolds. In the n = 2 case, we present some evidence that turning on such terms resolves the orbifold singularities and may lead to a K...

2017
Dinesh Rakheja Kenneth S. Chen Yangjian Liu Abhay A. Shukla Vanessa Schmid Tsung-Cheng Chang Shama Khokhar Jonathan E. Wickiser Nitin J. Karandikar James S. Malter Joshua T. Mendell James F. Amatruda

Journal: :iranian journal of child neurology 0
seyed hassan tonekaboni 1. professor of pediatric neurology, pediatric neurology research center, shahid beheshi university of medical science, tehran, iran 2. professor of pediatric neurology, school of medicine, hahid beheshi university of medical science, tehran, iran ahmad ebrahimi phd of medical genetic, parseh medical genetics center, tehran, iran mohammadkazem bakhshandeh bali pediatric neurology research center, shahid beheshti university of medical sciences, tehran, iran massoud houshmand phd of medical clinical genetic, national institute of genetic engineering and biotechnology, tehran, iran mehdi moghaddasi neurologist, department of neurology, rasool-e-akram hospital, tehran university of medical sciences, tehran, iran mohammad mahdi taghdiri associate professor of pediatric neurology, shahid beheshti university of medical science, tehran, iran

how to cite this article: tonekaboni sh, ebrahimi a, bakhshandeh bali mk, houshmand m, moghaddasi m, taghdiri mm, nasehi mm. sodium channel gene mutations in children with gefs + and dravet syndrome: a cross sectional study. iran j child neurol. 2013 winter; 7 (1):25-29.   objective dravet syndrome or severe myoclonic epilepsy of infancy (smei) is a baleful epileptic encephalopathy that begins ...

Journal: :jundishapur journal of microbiology 0
vahdat poortahmasebi hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, ir iran reza malekzadeh digestive disease research center, shariati hospital, tehran, ir iran ghodratollah montazeri digestive disease research center, shariati hospital, tehran, ir iran ehsan fakhari hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, ir iran mehdi norouzi hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, ir iran azam khamseh hepatitis b molecular laboratory, department of virology, school of public health, tehran university of medical sciences, tehran, ir iran

conclusions presence of drug resistance mutations among the patients was significant. precore mutations were common amongst iranian hbv chronic carriers under lamivudine therapy and these mutations were accompanied by clinical relapse. patients and methods sequential sera were obtained from 88 chronic hbv carriers who received lamivudine for more than 24 months. polymerase and precore regions w...

Journal: :international journal of pediatrics 0
masoud dehghan tezerjani reproductive and genetic unit, yazd research and clinical center for infertility, shahid sadoughi university of medical sciences, yazd, iran mohammad yahya vahidi mehrjardi medical genetic research center, shahid sadoughi university of medical sciences, yazd, iran seyed mehdi kalantar reproductive and genetic unit, yazd research and clinical center for infertility, shahid sadoughi university of medical sciences, yazd, iran mohammadreza dehghani medical genetic research center, shahid sadoughi university of medical sciences, yazd, iran

neonatal diabetes mellitus (ndm) is a rare kind of diabetes characterized by hyperglycemia and low levels of insulin. clinically, it is categorized into two main types: transient ndm (tndm) and permanent ndm (pndm). these types are diagnosed based on duration of insulin dependence early in the disease. in tndm, diabetes begins in the first few weeks of life with remission in a few months. howev...

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