نتایج جستجو برای: mutagenicity

تعداد نتایج: 3111  

Journal: :Gut 1984
D L Morris D Youngs T J Muscroft J Cooper C Rojinski D W Burdon M R Keighley

Mutagenicity has been measured in the gastric juice of 228 patients using the Ames bacteriological test system; while mutagenicity in control and duodenal ulcer patients did not differ from saline controls, mutagenicity was significantly increased compared with controls in patients suffering gastric ulcer (p less than 0.002), carcinoma (p less than 0.002), and in patients after gastric resectio...

Journal: :Environmental Health Perspectives 1994
R Barale L Giromini S Del Ry B Barnini M Bulleri I Barrai F Valerio M Pala J He

The mutagenicity of airborne particulate matter collected in 17 towns of Italy in 1990 was assessed using the Ames test. The mutagenicity of crude extract correlated with amount of lead, suggesting the direct contribution of gasoline car exhausts. Moreover, the mutagenicity correlated with particulate matter amounts. An inverse correlation with temperature was observed. The crude extracts were ...

Journal: :iranian journal of pharmaceutical research 0
masoomeh heshmati department of biology,science and research branch, islamic azad university sepideh arbabi bidgoli department of toxicology and pharmacology,pharmaceutical sciences branch,islamic azad university samideh khoei medical physics department, school of medicine, iran university of medical sciences, tehran, iran. seyed mahdi rezayat department of toxicology and pharmacology, faculty of pharmacy, pharmaceutical sciences branch, islamic azad university, tehran, iran. department of pharmacology, school of medicine, tehran university of medical sciences, tehran, iran kazem parivar department of biology, science and research branch, islamic azad university

serious concerns have been expressed about potential health risks of nano silver containing consumer products (agnps) therefore regulatory health risk assessment on such nanoparticles has become mandatory for the safe use of agnpsinbiomedicalproducts with special concerns to the mutagenic potentials. in this study, we examined the inhibitory and mutagenicity effects of agnps in three different ...

Journal: :Cancer research 1989
M H Schiffman A W Andrews R L Van Tassell L Smith J Daniel A Robinson R N Hoover J Rosenthal R Weil P P Nair

Fecal mutagenicity was measured in 68 patients with colorectal cancer and in 114 controls, using Salmonella tester strains TA98 and TA100 with and without S9 activation. Samples were also tested for fecapentaenes by high-performance liquid chromatography, to permit the separation of fecapentaene and non-fecapentaene mutagenicity. Overall, no significant case-control differences in fecal mutagen...

2006
Mark H. Schiffman A. W. Andrews Roger L. Van Tassell Lee Smith James Daniel Adam Robinson Robert N. Hoover Jeanne Rosenthal Roselyn Weil Padmanabhan P. Nair Samuel Schwartz Hugh Pettigrew Gerald Batist Roger Shaw Tracy D. Wilkins

Fecal mutagenicity was measured in 68 patients with colorectal cancer and in 114 controls, using Salmonella tester strains TA98 and TA 100 with and without S9 activation. Samples were also tested for fecapentaenes by high-performance liquid Chromatograph), to permit the sepa ration of fecapentaene and non-fecapentaene mutagenicity. Overall, no significant case-control differences in fecal mutag...

Journal: :Japanese Journal of Pharmacology 1977

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000
R Vermeulen H Wegh R P Bos H Kromhout

Lifestyle factors such as smoking have been shown to influence urinary mutagenicity. Therefore, these factors have to be considered carefully when evaluating occupational genotoxic exposures. We investigated day-to-day variability in active and passive tobacco smoke exposure by studying urinary cotinine levels and determined their influence on observed urinary mutagenicity. Urinary cotinine was...

Journal: :Journal of applied microbiology 2003
G Wegrzyn A Czyz

One of the most important and serious ecological problems is mutagenic pollution of the natural environment. Therefore, detection of mutagenic compounds in samples taken from natural habitats is of special interest. Microbiological mutagenicity tests seem to be very useful tools for such detection. In this review article, a general view on the tests employing genetically modified bacterial stra...

Journal: :jundishapur journal of natural pharmaceutical products 0
heibatullah kalantari school of pharmacy, toxicology research center, jundishapur university of medical sciences, ir iran +98-6113362197, [email protected]; school of pharmacy, toxicology research center, jundishapur university of medical sciences, ir iran +98-6113362197, [email protected] hamid galehdari school of pharmacy, toxicology research center, jundishapur university of medical sciences, ir iran +98-6113362197, [email protected] zahra zaree school of pharmacy, toxicology research center, jundishapur university of medical sciences, ir iran +98-6113362197, [email protected] hadi kalantar school of pharmacy, toxicology research center, jundishapur university of medical sciences, ir iran +98-6113362197, [email protected] golnaz varnasary school of pharmacy, toxicology research center, jundishapur university of medical sciences, ir iran +98-6113362197, [email protected]

background the increasing use of herbal drugs and their easy availability have necessitated the use of mutagenicity tests to analyze their toxicity and safety. objectives the aim of this study was to determine the in vitro mutagenicity of artemisia draconculus l., a herbal drug, by performing single cell gel electrophoresis (scge). materials and methods in this study, we obtained a herbal drug ...

بهبهانی, ماندانا, خواجه زاده, سارا,

Background and purpose: Avicennia marina (family Acanthaceae) has been used as traditional medicine in Iran to treat some diseases such as ulcers, rheumatism and burns. The present study investigated the in silico and in vitro mutagenicity of the fruit, leaf, seed and stem extracts of Avicennia marina and their effects on human peripheral blood mononuclear cells (PBMC) proliferation. Materia...

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