when stretcher came to unit and i was put in my bed, nursing personnel of surgical ward said to me hello. i had seen their face from yesterday night when they were transferring patients from emergency ward to this unit.  in that time, i had the role of emergency ward assistant manager. today, i am a weak patient that even is unable for smallest movement. cause of my admission to hospital is mus...

purpose: to evaluate demographics and therapeutic outcomes of patients with third nerve palsy who had been treated between 1999 to 2009 at labbafinejad medical center. methods: in this retrospective study, we evaluated 52 patients with third nerve palsy who had been referred to labbafinejad medical center over a ten-year period. results: in this retrospective study, subjects who had been treate...

permanent facial paralysis is a catastrophic event for involved patients. in long lasting paralysis with severe facial muscles atrophy, masseter muscle transfer is a very good choice. but its greatest problem is postoperative elongation of flap and gradual diminishing of early results and loss of symmetry. this article advocate a new modification for resolving this problem with concomitant elev...

Permanent facial paralysis is a catastrophic event for involved patients. In long lasting paralysis with severe facial muscles atrophy, masseter muscle transfer is a very good choice. But its greatest problem is postoperative elongation of flap and gradual diminishing of early results and loss of symmetry. This article advocate a new modification for resolving this problem with concomitant el...

1. Hypokalaemic periodic paralysis is characterized by attacks of muscle weakness. Glucose, insulin and an abnormal regulation of ATP-sensitive potassium channels may be involved in these attacks. We studied the effect of hyperglycaemia and of the potassium channel opener pinacidil on insulin release and muscle strength in patients with hypokalaemic periodic paralysis. 2. Insulin release was as...

The Guillain Barre Syndrome (GBS) is an acute immune mediated progressive polyneuropathy having monophasic illness leading to paralysis. clinical features are ascending symmetrical muscle weakness that may lead respiratory failure. Diagnosis based upon presentation and supported by a lumbar puncture with CSF analysis demonstrating albumin cytological dissociation electrophysiological studies. O...

Transient muscle paralysis engendered by a single injection of botulinum toxin A (BTxA) rapidly induces profound focal bone resorption within the medullary cavity of adjacent bones. While initially conceived as a model of mechanical disuse, osteoclastic resorption in this model is disproportionately severe compared with the modest gait defect that is created. Preliminary studies of bone marrow ...

An abnormal ratio between Na+ and K+ conductances seems to be the cause for the depolarization and paralysis of skeletal muscle in primary hypokalemic periodic paralysis. Recently we have shown that the "K+ channel opener" cromakalim hyperpolarizes mammalian skeletal muscle fibers. Now we have studied the effects of this drug on the twitch force of muscle biopsies from normal and diseased human...

background & objective:  periodic paralyses are a group of rare disorders that cause temporary episodes of muscle weakness or paralysis.  hypokalemic periodic paralysis usually is transmitted by an autosomal dominant trait with more penetration in men.  hypokalemic periodic paralysis may be secondary to thyrotoxicosis, hyperparathyroidism, drug  toxicity and potassium losing states. sporadic fo...