muscle biopsy has been used for a long time for diagnosis of muscular, nerurogenic and systemic disorders with muscle involvement, because only very few of these disorders show sufficient specific clinical features for definite diagnosis. since the presence of difficulties in the screening of numerous genes, muscle biopsy could be a time and cost effective procedure for solving the diagnostic p...

Muscle biopsy has been used for a long time for diagnosis of muscular, nerurogenic and systemic disorders with muscle involvement, because only very few of these disorders show sufficient specific clinical features for definite diagnosis. Since the presence of difficulties in the screening of numerous genes, muscle biopsy could be a time and cost effective procedure for solving the diagnostic p...

in this report we are going to discuss the following subjects: 1. indications of muscle biopsy in which situation it can not be helpful. 2. how to take a muscle biopsy? 3. how a muscle biopsy should be operated? 4. which techniques do we need to read and interpret a muscle biopsy histologically (h & e staining, histochemical study, electron microscopy). 5. muscle disease histopathologic changes...

how to cite this article: nilipor y, shariatmadari f, abdollah gorji f, rouzrokh m, ghofrani m, karimzadeh p, taghdiri mm,  delavarkasmaei h, ahmadabadi f, bakhshandeh bali mk, nemati h, saket s, jafari n, yaghini o, tonekaboni sh.  evaluation of one hundred pediatric muscle biopsies during a 2-year period in mofid children and toos hospitals. iran j child neurol. 2013 spring;7(2):17-21.   obje...

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Muscle and nerve biopsy may be vital diagnostic tools in various neuromuscular disorders. Since these procedures are invasive, it matters to decide when perform a biopsy, which muscle or selected, how interpret the pathologies. This review addresses indications, methods of biopsies, also significant pathological findings frequently encountered pathology.

a 75-year-old woman presented with six months history of progressing lagophthalmos and immobility of the left eye. magnetic resonance imaging (mri) of the orbit demonstrated infiltration of orbital fat and the extra-ocular muscles. we performed transverse blepharotomy of the left eyelid to correct lagophthalmos; and during surgery, we took a biopsy sample from levator muscle and orbital fat. af...