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sepsis is the systemic response to severe infection in critically ill patients. sepsis, septic syndrome & septic shock represent the increasingly severe stages of the same disease. despite the remarkable improvements in outcome, sepsis & septic shock remain an important cause of morbidity & mortality in children. this is a retrospective study among the patients who were admitted in the pediatri...

background: renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. the aim of this study was to determine the final outcome of renal involvement in leptospirosis. methods: this longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. all patients we...

INTRODUCTION EPIDEMIOLOGY The Civilian Experience The Military Experience Traumatic Injury Trauma-Related Sepsis and Septic Shock Cellular and Subcellular Mechanisms Leading to SIRS/MODS Components and Products From Microorganisms Giving Rise to SIRS/MODS Cellular Components Contributing to SIRS/MODS Endogenous Mediators ORGAN-SPECIFIC RESPONSES Cardiovascular Response Pulmonary Response Renal ...

Autoimmune polyendocrine syndromes are a heterogeneousgroup of rare diseases characterized by autoimmune activityagainst more than one endocrine organ, although non-endocrineorgans can also be affected. We report the association of APS Iwith erythema annulare centrifugum in an 18-years-old male whopresented with multiple figurate erythema spreading on his trunkand extremities along with a histo...

BACKGROUND AND OBJECTIVES Hantavirus infection is a zoonose with worldwide distribution. The transmission is related to the intimal contact with rodents. It causes two syndromes: hemorrhagic fever with renal syndrome (HFRS), endemic in Asia and Europe and the Hantavirus pulmonary syndrome (HPS), found in the American continent, including Brazil, with high mortality rates. The aim of this study ...