objective(s): this study describes the preparation, biodistribution of 153sm-dtpa-spion after intravenous injection in rats. materials and methods: the chelator dtpa dianhydride was conjugated to spion using a small modification of the well-known cyclic anhydride method. conjugation was done at a 1: 4 (spion: ccdtpa) molar ratio. conjugation reaction was purified with magnetic assorting column ...

cardiac magnetic resonance imaging (cmri) is a well-established noninvasive imaging modality in clinical cardiology. its ability to provide tissue characterization make it well suited for the study of patients with cardiac diseases. we describe a multi-modality imaging evaluation of a 45-year-old man who experienced a near drowning event during swimming. we underline the unique capability of ti...

Pheochromocytoma, a rare neuroendocrine adrenal tumor, is often diagnosed by a combination of clinical, laboratory, and radiographic features. While the imaging features of this entity are variable, the use of complementary modalities often helps to target the diagnosis and assess the extent of the disease. We present a multi-modality evaluation of a pheochromocytoma, with CT, MR, MIBG, and pat...

ABSTRACT Measurement of breast tissue response to external stimulation has the potential to unveil additional dynamic biomarkers of disease states. Recently tumor contrast generated by breathing-gas induced vascular changes has been demonstrated using both BOLD imaging [1] and MRIguided near infrared diffuse optical tomography [2]. At the same time, in the biomedical optics community, temporall...